Polycystic kidney disease is a genetic kidney disease, polycystic kidney disease increase with age, the cysts gradually increased, the first performance: lower back pain, high blood pressure, abnormal renal B results, if not timely control kidney cysts continue to increase, and oppression around the renal unit will cause injury to start the process of renal fibrosis, will show as urine tests appear: leakage of protein and blood cells; renal fibrosis process has not been effective in deterring appears elevated serum creatinine or glomerular filtration rate, and ultimately develop into end-stage renal failure.
The nephropathy experts, polycystic kidney disease is not only influenced by genetic factors, and the age of the patient at the same time, the geographical location is also certain. Hereditary polycystic kidney disease can be divided into two types: adult polycystic kidney disease is autosomal dominant infantile polycystic kidney disease is autosomal recessive.
Numerous cysts polycystic kidney Department of the renal cortex and medulla of a hereditary disease. The kidney specialists pointed out that the mode of inheritance can be divided into autosomal dominant polycystic kidney and autosomal recessive polycystic kidney disease.
Adult polycystic kidney disease Genetic incidence of approximately 0.2%, mainly in the kidney cysts, increased development and the number of characterized, often accompanied by other organs cyst formation, most common liver, pancreatic, ovarian, and gastrointestinal tract can also be seen.
Autosomal recessive polycystic kidney genetic rule is: both parents heterozygous and homozygous offspring incidence, the incidence probability of 25%. Gender and racial differences.
The etiology of polycystic kidney disease autosomal dominant polycystic kidney genetic laws: female incidence probability thought; either parent for sick children 50% of cysts gene and the disease, if the parents are sick, the increase in the incidence of children to 75%; sick children do not carry the cysts genes.
So, polycystic kidney disease genetic risk is still high, there are the polycystic kidney women for our children's health, it is best not pregnant.
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