Renal insufficiency, hormone therapy: People know that renal insufficiency is often the use of hormone drugs, then the hormone have any therapeutic effect of renal insufficiency? Hormones on renal dysfunction and what side effects? Patients with renal insufficiency have more comprehensive understanding.
Adrenal cortical hormone, referred to as hormone, anti-inflammatory, stable lysosomes, immuno-suppression, increasing the activity of the Department of the glomerular capillary membrane, improving renal insufficiency, glomerular permeability and reduce the leakage of urine protein, so has a diuretic, eliminate protein and protection of renal function in patients with impaired renal function in the role. Large doses of hormones can increase the glomerular filtration rate, and inhibition of antidiuretic hormone, is the drug of choice for Western patients with renal insufficiency, some of the other kidney disease treatment commonly used drugs. But serious side effects may occur in the process of hormone therapy, common side effects are as follows:
(1) infection:
Susceptibility to infection in patients with renal insufficiency in the process of hormone use, and often mask the early symptoms of infection, large doses of hormone therapy should be prevention of infection attention to the pharynx, nose, ears, urinary tract, skin, lungs, abdominal cavity, etc. infection, if found to be infected, the early use of antibiotics.
(2) rows of potassium sodium retention:
Long-term use of hormones in patients with renal insufficiency, attention should be paid to supplement the corresponding amount of potassium salt, eat more fruits and reduce the intake of salt, if necessary, service row natriuretic drug.
(3) acute adrenal insufficiency:
Long-term use of hormone therapy can be caused by endogenous adrenal cortical hormone secretion in patients with renal dysfunction by the inhibition of infection, can cause acute adrenal dysfunction Therefore, patients with renal insufficiency in the process of application of hormone therapy, a doctor under the guidance, not to reduce or stop the medication.
(4) bleeding and gastric perforation:
Merger stomach, duodenal ulcer disease or gastrointestinal bleeding in patients with renal insufficiency, large doses of hormones could easily cause bleeding or perforation, so that those patients with ulcer disease, as far as possible with the use of small doses of hormones and the treatment of ulcer drug, and often Note that the stool color and check for occult blood.
(5) a hypercoagulable state and Thrombosis:
The hormone may increase the tendency of renal insufficiency in patients with a hypercoagulable state and concurrent embolization, Guchang combination of anticoagulants or traditional Chinese medicine. Prevention and treatment of renal vein thrombosis and cerebral embolism.
(6), renal dysfunction and blood pressure:
Hormone treatment of adult patients with renal insufficiency, renal dysfunction, high blood pressure side effects. Therefore, the renal dysfunction associated with nitrogen retention should be used with caution.
Because of the serious side effects of hormone therapy, combined with the hospital experience in clinical practice, it is recommended in patients with kidney disease occurred in the early use of hormone therapy at the same time, we must as soon as possible involved in micro-technology medicine penetrate therapy until the final instead of hormone therapy to reduce or avoid side effects occurred.
Kidney disease experts recommend the use of stem cell transplantation for treatment of kidney disease - the stem cells is a strong self-replicating and multiple differentiation ability to repair cells, it enters the body will be strong to repair damaged cells function in kidney patients, there is a strong recovery of renal function capacity. Therefore, kidney disease for patients with stem cell transplantation is an effective means of treatment. The one hand, the maximum stem cell therapy to repair damaged kidney cells in the lesions of blocking the renal fibrosis process, lower serum creatinine, and reduce the complications of renal anemia, hypertension, renal edema, but also allows protein, occult blood, and other indicators decreased or even negative, can prolong dialysis time interval, or even get rid of dialysis, regulate and control the primary disease. Even in late renal failure, uremia, the implementation of stem cell therapy, are also viable options.Stem cell therapy will be as much as possible as a supplementary treatment to repair damaged kidney cells to protect the residual renal cell, renal function. But also in conjunction with other effective treatment for reversal of lesions occur renal cell dialysis interval to extend and improve the complications, slow down the process of kidney failure, and improve the quality of life
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