Normal fluctuation in blood pressure is adaptive and necessary. Fluctuations
in pressure that are significantly greater than the norm are associated with
greater white matter hyperintensity, a finding consistent with reduced local
cerebral blood flow and a heightened risk of cerebrovascular disease. Within
both high- and low-blood pressure groups, a greater degree of fluctuation was
found to correlate with an increase in cerebrovascular disease compared to those
with less variability, suggesting the consideration of the clinical management
of blood pressure fluctuations, even among normotensive older adults. Older
individuals and those who had received blood pressure medications were more
likely to exhibit larger fluctuations in pressure.
Fluctuating blood pressure has two different modes. In one, the pressure goes up and in the other it goes down. When the fluctuation is on the higher side, it means that the heart is trying hard and putting in extra efforts to pump out the blood. Some of the factors that can be responsible for it are as follows:
Hypertension: One of the main causes behind fluctuation is hypertension. This may happen due to some undiagnosed heart disease. Other medical conditions like kidney disease, hormonal problems, pregnancy can contribute to hypertension. In some cases, hypertension runs in the family.
Stress: Stress and anxiety are the other two major causes of fluctuating blood pressure. It has been found that seventy percent of people cannot keep their blood pressure normal just because they fail to manage their stress level.
Side Effects of Medicines: There are a number of prescription or over the counter medicines that can lead to this condition. It includes birth control pills, pain relieving medicines, antidepressants, common cold medicines and so on. Illegal drugs like cocaine also have adverse effect on the blood pressure.
How to treat Fluctuating Blood Pressure
Step 1: Further tests. There is no immunofluorescence in your biopsy report, so we don't know what kind of immune complex deposited on the kidneys and what's the exact amount. I suggest you do Circulating Immune Complex (CIC) to find out and subgroup lymphocytes to see the immune reaction in your body. Only if we make everything clear of the disease can we use medicine scientifically and treat it targetedly and effectively.
Step 2: Blocking immune reaction. Your biopsy shows inflammatory cells infiltrating. We have to stop the inflammation in the kidneys and stop the renal fibrosis. According to scientific diagnosis, the medicine, dose and duration will be very exact. Scientific use of immunosuppressants will well control the immune reaction in the kidneys.
Step 3: Immune tolerance. As the disease often relapses, we have to assess the disease condition before inflammation in the kidneys becomes serious again. Giving small dose of immunosuppressants regularly can prevent the relapse of the disease. This is to let our body accept the fact that there is immune complex in the kidneys and the antibodies will stop attacking them temporarily.
Fluctuating blood pressure has two different modes. In one, the pressure goes up and in the other it goes down. When the fluctuation is on the higher side, it means that the heart is trying hard and putting in extra efforts to pump out the blood. Some of the factors that can be responsible for it are as follows:
Hypertension: One of the main causes behind fluctuation is hypertension. This may happen due to some undiagnosed heart disease. Other medical conditions like kidney disease, hormonal problems, pregnancy can contribute to hypertension. In some cases, hypertension runs in the family.
Stress: Stress and anxiety are the other two major causes of fluctuating blood pressure. It has been found that seventy percent of people cannot keep their blood pressure normal just because they fail to manage their stress level.
Side Effects of Medicines: There are a number of prescription or over the counter medicines that can lead to this condition. It includes birth control pills, pain relieving medicines, antidepressants, common cold medicines and so on. Illegal drugs like cocaine also have adverse effect on the blood pressure.
How to treat Fluctuating Blood Pressure
Step 1: Further tests. There is no immunofluorescence in your biopsy report, so we don't know what kind of immune complex deposited on the kidneys and what's the exact amount. I suggest you do Circulating Immune Complex (CIC) to find out and subgroup lymphocytes to see the immune reaction in your body. Only if we make everything clear of the disease can we use medicine scientifically and treat it targetedly and effectively.
Step 2: Blocking immune reaction. Your biopsy shows inflammatory cells infiltrating. We have to stop the inflammation in the kidneys and stop the renal fibrosis. According to scientific diagnosis, the medicine, dose and duration will be very exact. Scientific use of immunosuppressants will well control the immune reaction in the kidneys.
Step 3: Immune tolerance. As the disease often relapses, we have to assess the disease condition before inflammation in the kidneys becomes serious again. Giving small dose of immunosuppressants regularly can prevent the relapse of the disease. This is to let our body accept the fact that there is immune complex in the kidneys and the antibodies will stop attacking them temporarily.
