What are the similarities of them?
▲ Both IgA Nephropathy and Allergic Purpura Nephritis have the deposition of IgA in the glomeruli.
▲ The concentration of IgA in the serum arises obviously in both of the diseases.
▲ The IgA in the peripheral lymphocytes will increase no matter which kind of the two diseases people get.
▲ The quantity of immune complex in serum is similar between the two diseases.
Nevertheless, these things can not prove IgA Nephropathy and Allergic Purpura Nephritis belong to the same kind of kidney disease. There are also some differences between them.
▼ IgA Nephropathy is always found in young adult, while Allergic Purpura Nephritis mainly attack children who are 5 to 15 years old.
▼ At the early stage of the disease, IgA Nephropathy are symbolized by repeated hematuria and asymptomatic protein, but Allergic Purpura Nephritis will lead to many changes in the body and the symptoms are similar to Nephritis and Nephritic Syndrome.
▼ The symptoms of IgA in clinic are not closely attach with the pathological changes in the kidneys, however, the prognosis and the manifestations of Allergic Purpura Nephritis are closely related to the tissue changes in the kidneys.
▼ The degree of infiltration of renal tissues can affect the quantity of proteinuria if the patients are suffering from IgA Nephropathy, but Allergic Purpura Nephritis do not have this relationship.
▼ If the condition of disease is stable, the mononuclear cells infiltration can be remitted in the patients with Allergic Purpura Nephritis, but not in the patients with IgA Nephropathy.
▼ IgA Nephropathy is chronic disease, and Allergic Purpura Nephritis is acute, which also tell us to pay attention to the differences when doing diagnosing and prognosis of the two diseases
