Basing on the investigation, more than 90% of the IgAN sufferers are sporadic, which means that the majority of the patients get the IgAN occasionally. The rest ten percent people have a trend of family gathering, and it is more common in certain areas such as the south part of United State, France and Italy.
In addition, the morbidity of IgA Nephropathy varies in different races. It seems that Asian and Hispanics are more likely to have IgAN than those who are American Indians. Even so, the whites in American suffer less morbidity than the African Americans do.
People may wonder why the IgA is not hereditary while being called an immune system disease.
IgAN is caused by the disorder in immune system in the patients’ body, characterized by the deposition of immune complex in the glomerular area. The disorder of immune system makes the patients have less ability to fight against the bacterium and toxin both internally and externally, thus little infection and wounds can lead to imbalance of immune system in the body and then cause IgAN.
However, it does not mean that IgAN is hereditary. The occurrence of the disease depends on the condition of the immune system in the body, and the patients with IgAN can also have a baby with a strong immune system as long as the mother followed the suggestion of the doctors before pregnancy.
