Why does Nephrotic syndrome with edema ?


Edema is a common symptom of nephrotic syndrome, nephrotic syndrome edema What are the reasons for it? Timely understand the reason, only do symptomatic treatment of the disease, making treatment to obtainthe best results. Nephrotic syndrome edema reasons:
1 tube imbalance
The ball refers to the glomerulus, the management refers to tubular kidney's main quality is primarily by renal unit, renal unit and part of the glomerular and tubular components. Under normal circumstances, the glomerular filtration of water, salts and other substances, 99% were tubular reabsorption by, so that the body is small and the dielectric to maintain the relative dynamic equilibrium. When the kidney disease, the tube imbalance, on the one hand the glomerular filtration rate for water, sodium loss, on the other hand, the tubular reabsorption of water, sodium does not decrease, resulting in the body of water, sodium retention caused by edema. Such a situation is seen most glomerulonephritis.
2, hypoproteinemia
Kidney disease, glomerular basement membrane permeability-increasing protein from the urine induced plasma protein concentration decreased plasma osmotic pressure, the liquid begins with the blood vessels penetrate the protein is relatively high organization of the interosseous membrane, causing edema. The protein is an important material to maintain the plasma osmolality, plasma protein concentration decreased plasma osmolality. Water go to the high osmotic pressure caused by edema.
3, hormones, endocrine causes
Kidney disease, endocrine function is often secondary changes, such as aldosterone, estrogen, such as increased, can be caused by a body of water, sodium retention caused by or exacerbated by nephrotic edema.
Kidney disease due to renal erythropoietin hormone to reduce, causing anemia: anemia lead to renal ischemia, renal ischemia, renin secretion caused by increased blood pressure. Anemia, hypertension coupled with nephropathy metabolites retention stay and decreased immunity, secondary to cardiac dysfunction, which in turn cause of the edema. This is common in chronic renal insufficiency and uremia patients.

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