● Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.
● Autosomal Dominant PKD (ADPKD) is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.
Patients get ADPKD from their parents, which means that they are carrying the factors of the disease from the very beginning of their life, but their disease can be found after they grow up. ADPKD can attack a family easily due to its character of heredity. Half of the children may have the disease if one of the parents has PKD, and the percentage will get up to 75% if both of parents have the disease. This is also a key factor which should be noticed, if one of the family members has PKD, other members should be careful and try to delay the occurrence of it.
Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.