Lump in Abdomen: Patients with Polycystic Kidney Disease can feel the different size of lumps in midsection when kidneys enlarge to a certain degree. These lumps can move with the breath and when these lumps cause infections, patients with Polycystic Kidney Disease will feel pain in their belly. About fifty percent to eighty percent of patients have bilateral pumps and fifteen percent to thirty percent of patients can feel unilateral lumps.
High blood pressure: High blood pressure is one of the common symptoms for patients with Polycystic Kidney Disease, and usually fifty percent to sixty percent of patients have this symptom. High blood pressure usually is prior to the decrease of renal function and is accompanied with headache and dizziness. Blood pressure has a close relationship with type Ⅱ angiotension which is aimed at shrinking blood vessels. When renal function is damaged, renin in our body increase, which will promote the generation of type Ⅱangiotension, leading to the increase of blood pressure.
Discomfort of waist and belly: Usually, discomfort of waist and belly appears in the early stage of Polycystic Kidney Disease. It mainly manifest with dull pain of back and sometimes severe pain.