Then, how does high blood pressure damage kidneys? In the early stage, it is the simple hypertension, but when it is not well controlled, the arterial tension rises constantly, and there may be high pressure and great filtration within glomeruli. With the development of hypertension, the structure of renal arteriole is changed so that the blood volume in it decreases, and then ischemia and anoxia of kidneys appear. The endothelial cells in glomeruli are damaged thereby. These damaged endothelial cells promote the accumulation of hematoblast and help to form the thrombus. Some factors will be excreted from them to attract inflammatory cells infiltrate into mesangial regions and damage glomerular functions. Therefore, renal fibrosis begins.
During this period, Renal Insufficiency may happen if the process can not be prevented fundamentally. This is also the reason why Hypertensive Nephropathy reoccurs often in clinic. Western medicine can only reduce the blood pressure and remit the urinary protein, but the root of the disease cannot be treated.
