IgA nephropathy treatment principle of analytic
IgA nephropathy is a glomerular mesangial deposition of IgA or IgA deposition mainly primary glomerular diseases. IgA nephropathy in the characteristics of the disease clinically, IgA nephropathy is more common in young people (under 35 years of age), the incidence of male-dominated, multi-gross hematuria and treatment.
IgA nephropathy is the most common and most important pathogenesis of glomerular mucosal immune dysfunction. Due to defects of the mucosal immune function, a large number of IgA deposition in the glomerular mesangial area. Combined with the blood of patients with IgA nephropathy compared with normal lack of glycosylation can not be combined with IgA glycosylation, a large number of IgA deposition. Deposition in the glomerular mesangial area of IgA makes the kidney inherent cell damage, thus triggering the occurrence of renal fibrosis process. Among them, renal inherent cell injury in glomerular mesangial cells start factor for renal fibrosis.
In addition, because a large number of clustering of IgA, coupled with the phenotype of renal intrinsic cells to transformation, making the glomerular capillary narrowing, effective glomerular perfusion pressure reduced glomerular effective filtration rate, and gradually make the glomerular , renal vascular fibrosis and sclerosis.
The occurrence of microcirculation due to the aggregation of IgA in the glomerular kidney micro-thrombosis, muscle fibroblasts, the occurrence of these conditions will further promote glomerular fibrosis, hardening.
Proceed from the starting etiology of IgA nephropathy, a fundamental treatment of IgA nephropathy. Infiltration therapy, micro-based traditional Chinese medicine for kidney mucosal immune dysfunction specific repair, repair the mucous membrane of the variation in kidney function returned to normal, so that to avoid IgA deposition in mesangial. Meanwhile, the micro of traditional Chinese medicine to penetrate therapy targeting glomerular mesangial IgA, so that the degradation. Thus, reversal of Renal cell phenotype, blocking the process of renal fibrosis.
Micro therapy for the penetration of traditional Chinese medicine to dilate blood vessels, expansion at all levels in the kidney blood vessels, effectively relieve renal ischemia caused by renal vasoconstriction, hypoxia, and the glomerular effective filtration feature enhanced clinical performance reduce leakage in patients with proteinuria, hematuria reduce.
Micro-based traditional Chinese medicine penetrate therapy can improve the patient's body microcirculation, promote the body's blood circulation, originally due to kidney blood circulation disorders caused by systemic hypoxia symptoms can be improved effectively reduce the symptoms of systemic poisoning of the patient's clinical manifestations of the patient's urine creatinine increase, the body puffiness subsided, improve symptoms of anemia, increased appetite.
Micro of traditional Chinese medicine to penetrate therapy can promote myofibroblast apoptosis has been formed within the kidney, thereby blocking the process of renal fibrosis. The same time, have damage in the kidney unit can provide good repair, supplementary required for repair of various substances such as proteins, amino acids, vitamins, thus speeding up the damaged kidney function recovery.
The combination of micro-based traditional Chinese medicine infiltration therapy with other treatments to improve kidney, gastrointestinal, and systemic peripheral blood circulation, blocking renal fibrosis process, repair damage to the renal unit, a fundamental solution to the patient's disease status. And effectively to ensure its therapeutic effect, less recurrence.
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