What is the focal proliferative iga nephropathy?

Focal proliferative IgA nephropathy is a pathological manifestations of IgA nephropathy, IgA nephropathy III level, is a common report of the renal biopsy results. Pathological damage of focal proliferative IgA nephropathy in renal biopsy: about 50% of the glomerular cell proliferation, cell proliferation was initially limited to the mesangial area, or due to the capillary cell proliferation induced glomerular capillary loop obstruction, visible crescent, the vast majority of focal proliferative IgA nephropathy lesions showed glomerular segmental proliferation, some patients can be no such lesions; Under normal circumstances, renal tubules and renal interstitial lesions.
Focal proliferative IgA nephropathy pathological diagnosis
As we can see from the above pathological diagnosis, the renal biopsy have varying degrees of focal proliferative IgA nephropathy in patients with glomerular, tubular, renal interstitial lesions. Mesangial cell proliferation, crescent formation, tubular atrophy, renal interstitial fibrosis. This period, patients may manifest clinically increased leakage of urine protein, urine protein + - + + + ranging, and often hematuria. Clinical symptoms can also be edema, nausea, vomiting, severe cases can also be associated with elevated blood pressure, even progressive loss of renal function, the development of chronic renal insufficiency.
How to treat focal proliferative iga nephropathy
Micro-based traditional Chinese medicine active substances can inhibit mesangial cell proliferation and induce apoptosis; increase in effective renal vascular blood flow and promote blood circulation, so as to achieve the effect of the dilation of blood vessels to improve the status of renal tubular atrophy; increase the generation of degrading enzymes in the kidney, muscles leading to renal interstitial fibrosis, fibroblast degradation of these harmful substances smash patients excreted as urine, which is why there is sediment in the urine (also including excreted from the kidneys of immune complexes), one of the reasons.
The above course of treatment, common clinical manifestations of IgA nephropathy in patients with hematuria will slowly disappear, the protein leakage will be reduced. This is because the active substances of Chinese medicine in patients with renal permeability reduces the glomerular filtration rate has been well modified, making it the protein, urine red blood cell leakage to reduce, in patients with hematuria, proteinuria will gradually disappear. Blood pressure and other symptoms are the clinical signs of kidney damage kidney tissue of patients to be reversed, the corresponding clinical symptoms also improved, blood pressure gradually stabilized.
In short, focal proliferative IgA nephropathy is a common pathological type of IgA nephropathy, clinicians often receive patients with IgA nephropathy, patients with kidney function showed a downward trend, if not promptly be treated, but also may develop IgA nephropathy with chronic renal failure patients for focal proliferative IgA nephropathy confirmed by renal biopsy, it should be treated aggressively, or in the clinical symptoms described above should prompt renal biopsy.