Treatment of nephrotic syndrome
Nephrotic syndrome is a more stubborn symptoms, clinical treatment is very difficult.Nephrotic syndrome is not a disease name, it is a clinical syndrome caused by a variety of causes, the most basic is characterized by high proteinuria, hypoalbuminemia, edema and hyperlipidemia, clinical, known as the "three highs a low "symptoms.
Nephrotic syndrome in patients with renal mostly because the different factors in ischemia and hypoxia, resulting in local glomerular lesions caused by Therefore, in the treatment of nephrotic syndrome need to follow these guidelines:
, "At its source, vasodilator, an expansion of the renal artery at all levels to improve the local microcirculation, increase the effective perfusion, alleviate impaired renal hypoxia.Prevent the inflammatory response intensifies, and reduce the factors of glomerular damage.
2, inhibition of inflammatory mediators, cytokines and growth factors induced renal toxicity factor activity inactivated, thereby blocking the damaged kidney cells to continue to damage, prompted the reversal of the normal metabolic function, reduce glomerularpathological changes.
3, the Nephropathy comprehensive patients prone to hypoalbuminemia, resulting in blood concentration, the hypercoagulable high viscous state, lipoprotein Lp (a) inhibition of the fibrinolytic capacity increased fibrinogen activator to increase, increase in fibrin clot dissolution a reduced ability to cause thrombosis. Kidney disease expert pointed out that on the other hand, the kidney endothelial cells has anticoagulant, anti-thrombosis, renal ischemia and hypoxia, it will cause endothelial cell damage, platelet hyperfunction, increased platelet adhesion and aggregation, resulting in anticoagulant function will drop, thrombosis, and further development of renal fibrosis. Therefore, anticoagulant therapy should be promptly carried out to prevent the above from happening.
4, if nephrotic syndrome is not in the initial stages of renal fibrosis, effectively blocking later in the progression of renal fibrosis, the formation of the ECM to add to the cell damage of the kidney function, so this part of the extracellular matrix (ECM)decomposition, in order to block renal fibrosis, recovery of renal function.
In addition to these treatments follow the above principles, nephrotic syndrome, there are other treatments you? · Kidney disease hospital in kidney disease experts, a large number of clinical practice, successfully developed a pure Chinese medicine for the treatment of nephrotic syndrome of treatments ", features direct role of the pure Chinese medicine in the renal lesions, Chinese medicine active material expansion of the body at all levels of vascular, renal ischemia by increasing the effective systemic perfusion, the damaged cells of the blood supply, oxygen, fundamentally alleviate hypoxia, reducing the cells continue to damage kidney function. At the same time, the characteristics of pure Chinese medicine active ingredients can also play the following five-point role
To strengthen the metabolic function of cells, promote damage inherent in cell phenotype reversal to prevent its continued damage.
Two active substances of the characteristics of pure Chinese medicine has a two-body regulate immune function, inhibition of the damaged glomerular continue to immune-mediated injury.
3, inactivation of the characteristics of pure Chinese medicine active ingredients of the activity of a series of inflammatory mediators, cytokines, growth factors, the activity of inflammatory cells induced renal toxicity factor, reducing the infiltration of inflammatory cells and growth factors and chemokines the number to reduce the inflammatory response, prompted the reversal of the normal metabolic function.
Security into myofibroblasts and the apoptosis of immune complexes, blocking its continued synthesis and secretion of ECM.
5, increase the generation of degrading enzymes in the kidney, to promote ECM degradation, to reduce their damage to kidney tissue.
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