Treat kidney disease and diabetes: 十月 2011

Polycystic Kidney Disease of treatment

Polycystic Kidney Disease (PKD or PCKD, also known as polycystic kidney syndrome) is a cystic genetic disorder of the kidneys
Although a cure for autosomal dominant PKD is not available, treatment can ease symptoms and prolong life.
Pain. Pain in the area of the kidneys can be caused by cyst infection, bleeding into cysts, kidney stone, or stretching of the fibrous tissue around the kidney with cyst growth. A doctor will first evaluate which of these causes are contributing to the pain to guide treatment. If it is determined to be chronic pain due to cyst expansion, the doctor may initially suggest over-the-counter pain medications, such as aspirin or acetaminophen (Tylenol). Consult your doctor before taking any over-the-counter medication because some may be harmful to the kidneys. For most but not all cases of severe pain due to cyst expansion, surgery to shrink cysts can relieve pain in the back and sides. However, surgery provides only temporary relief and does not slow the disease's progression toward kidney failure.
Headaches that are severe or that seem to feel different from other headaches might be caused by aneurysms-blood vessels that balloon out in spots-in the brain. These aneurysms could rupture, which can have severe consequences. Headaches also can be caused by high blood pressure. People with autosomal dominant PKD should see a doctor if they have severe or recurring headaches-even before considering over-the-counter pain medications.
Urinary tract infections. People with autosomal dominant PKD tend to have frequent urinary tract infections, which can be treated with antibiotics. People with the disease should seek treatment for urinary tract infections immediately because infection can spread from the urinary tract to the cysts in the kidneys. Cyst infections are difficult to treat because many antibiotics do not penetrate the cysts.
High blood pressure. Keeping blood pressure under control can slow the effects of autosomal dominant PKD. Lifestyle changes and various medications can lower high blood pressure. Patients should ask their doctors about such treatments. Sometimes proper diet and exercise are enough to keep blood pressure controlled.
End-stage renal disease. After many years, PKD can cause the kidneys to fail. Because kidneys are essential for life, people with ESRD must seek one of two options for replacing kidney functions: dialysis or transplantation. In hemodialysis, blood is circulated into an external filter, where it is cleaned before re-entering the body; in peritoneal dialysis, a fluid is introduced into the abdomen, where it absorbs wastes and is then removed. Transplantation of healthy kidneys into ESRD patients has become a common and successful procedure. Healthy-non-PKD-kidneys transplanted into PKD patients do not develop cysts.
Although a cure for autosomal dominant PKD is not available, treatment can ease symptoms and prolong life.
Pain. Pain in the area of the kidneys can be caused by cyst infection, bleeding into cysts, kidney stone, or stretching of the fibrous tissue around the kidney with cyst growth. A doctor will first evaluate which of these causes are contributing to the pain to guide treatment. If it is determined to be chronic pain due to cyst expansion, the doctor may initially suggest over-the-counter pain medications, such as aspirin or acetaminophen (Tylenol). Consult your doctor before taking any over-the-counter medication because some may be harmful to the kidneys. For most but not all cases of severe pain due to cyst expansion, surgery to shrink cysts can relieve pain in the back and sides. However, surgery provides only temporary relief and does not slow the disease's progression toward kidney failure.
Headaches that are severe or that seem to feel different from other headaches might be caused by aneurysms-blood vessels that balloon out in spots-in the brain. These aneurysms could rupture, which can have severe consequences. Headaches also can be caused by high blood pressure. People with autosomal dominant PKD should see a doctor if they have severe or recurring headaches-even before considering over-the-counter pain medications.
Urinary tract infections. People with autosomal dominant PKD tend to have frequent urinary tract infections, which can be treated with antibiotics. People with the disease should seek treatment for urinary tract infections immediately because infection can spread from the urinary tract to the cysts in the kidneys. Cyst infections are difficult to treat because many antibiotics do not penetrate the cysts.
High blood pressure. Keeping blood pressure under control can slow the effects of autosomal dominant PKD. Lifestyle changes and various medications can lower high blood pressure. Patients should ask their doctors about such treatments. Sometimes proper diet and exercise are enough to keep blood pressure controlled.
End-stage renal disease. After many years, PKD can cause the kidneys to fail. Because kidneys are essential for life, people with ESRD must seek one of two options for replacing kidney functions: dialysis or transplantation. In hemodialysis, blood is circulated into an external filter, where it is cleaned before re-entering the body; in peritoneal dialysis, a fluid is introduced into the abdomen, where it absorbs wastes and is then removed. Transplantation of healthy kidneys into ESRD patients has become a common and successful procedure. Healthy-non-PKD-kidneys transplanted into PKD patients do not develop cysts.

How Do I Recovery from Polycystic Kidney Disease

This is a real story of my patients.

“I will never forget you, dear.” Ellis replied tearfully, “you are my only in this world”. Hearing this word, I could hardly repress my tears……

I am a young lady with Polycystic Kidney Disease, a genetic kidney disease. I knew I have the potential to get this disease from my childhood. However, when it came that day, I found it is so hard for me to accept this fact. After being diagnosed with Polycystic Kidney Disease, I spend a long time to think about myself, Ellis, and our future. I love Ellis, my smart and handsome husband, and I do not want him to feel sad, but facing this fact, what I can do?

After the fierce ideological struggle, in one morning, I mustered up my courage to told Ellis I have Polycystic Kidney Disease. I hoped he can forget me, however, after hearing his words, I decided to do everything possible to live……

From that day on, I tried every means to treat my disease; however, disappointingly, cysts have never ceased to enlarging. Even so, I will not give up. This month, when I arrived at Kidney Disease Hospital, my life was changed. I was given Chinese medicine which I do not quite believe before as the major treatment. A week later, I did another examination about my cysts, and when I glanced at the reports, I was shocked. I could hardly breathe. One of my cysts should shrink to 52*45mm mm from 55*46mm. I could not believe what I saw. In order to confirm the authenticity of this report, I did examination again. The fact is the result of two examination reports is same and this time I know I find the chance to lengnow my life.

Do You Know the Signs of Diabetic Nephropathy

Firstly, Diabetics may get up for the bathroom more often at night.

As we know, normal people have more urine in the day than that at night. The things will change if the renal tubules are damaged and the function of concentration decrease, which is a sign of pathological changes in the kidneys.

Secondly, proteinuria is also an earliest sign of Diabetic Nephropathy.

Albumin in the urine presents long before the usual tests done in your doctor's office which can show evidence of kidney disease, so it is vital for diabetic patients to do a regular check more often. The glomerular filtration rate (GFR) begins to decrease if the proteinuria lasts for a long period, and degree of the disease also closely relates to the quantity of the proteinuria.

Thirdly, High blood pressure is also one of the main symptoms of Diabetic Nephropathy. Among the patients with Type 1 Diabetes, the morbidity of Hypertension is same with that among normal people, while the patients with Type 2 Diabetes may suffer a higher risk of getting high blood pressure. In addition, patients with proteinuria are also easily to get Hypertension.

Fourthly, here are some other signs of Kidney Disease in patients with Diabetes, and you can scan them and check yourself.

1. Ankle and leg swelling, leg cramps

2. High levels of BUN and creatinine in blood

3. Less need for insulin or antidiabetic medications

4. Morning sickness, nausea and vomiting

5. Weakness, paleness and anemia

6. Itching

In the early stage, the signs are mainly about the decrease of renal function, for example, proteinuria, swelling, renal failure and anemia.

What is Creatinine?

Creatinine is the metabolic waste of muscle in our body which is mainly be excreted through glomeruli, and each 20mg muscle can produce one milligram creatinine each day. Creatinine can be produced both internally and externally. On one hand, the meat we ingest is the main source of external creatinine, while on the other, the metabolism of muscle is of the internal one. The level of creatinine will be constant if the meat intake and metabolism of muscle are steady.

● What can we expect from the level of creatinine?

Clinically, creatinine is a key factor when doing a test to know the function of kidneys. How does creatinine form and get out of the body? We have learned from the above that the internal creatinine comes from muscle. It is formed gradually during the irreversible non-enzyme dehydration, and then it is released into blood before excreted via urine. Therefore, creatinine level is close related to the amount of muscle in the body instead to the diet.

In addition, all the creatinine can be excreted out of the body no matter what the quantity of urine is, this is due to the fact that creatinine is such a micro molecule that it can easily get through the glomeruli. If the renal function is damaged, the creatinine can not pass the glomeruli freely, which will cause the accumulation of it in the body and be harmful to human body. The more the creatinine gathered, the severe the disease is. That is why we say that the creatinine level is an important factor to judge what degree the disease is in.

● What is the normal level of creatinine?

In the United States, creatinine is typically reported in mg/dL, whereas, in Canada and a few European countries, μmol/litre may be used. 1 mg/dL of creatinine is 88.4μmol/L.

The typical human reference ranges for creatinine are 0.5 to 1.0 mg/dL (about 45-90 μmol/L) for women and 0.7 to 1.2 mg/dL (60-110 μmol/L) for men. While a baseline creatinine of 2.0 mg/dL (150μmol/L) may indicate normal kidney function in a male body builder, a creatinine of 1.2 mg/dL (110μmol/L) can indicate significant renal disease in an elderly female. For male reference range are 60-120 μmol/L and for female it is 50-110 μmol/L (Ref: Australian Medicine Handbook)

Is Multiple Renal Cyst Same with Polycystic Kidney Disease

As one of the most common kidney diseases, Multiple Renal Cyst can occur in people with any ages. Most of the cysts are small and do not have any discomfort, however, there will appear some symptoms if the cysts are larger than 5cm, such as pain in the waist, frequent micturition, urgent urination, odynuria, hematuria.
Nevertheless, Multiple Renal Cyst is not the same with Polycystic Kidney Disease, and there are great differences between them.
The causes and the pathological changes are different. Polycystic Kidney Disease is a kind of autosomal inherited disease, while Multiple Renal Cyst can be inherited or the consequence of wounds, inflammatory reaction, tumour and so on.
Family history is an important factor. There must be some other people who have got similar disease in the family of a patient with Polycystic Kidney Disease, but the patient with Multiple Renal Cyst may not have this problem.
Substance in the cysts are not the same. Urine can always be found in the cysts of Polycystic Kidney Disease, however, the cysts of Multiple Renal Cyst may contain body fluid which is look like plasma and includes red blood cells in it.
Complications are different. Patients with Polycystic Kidney Disease have to suffer from many other diseases, such as Hypertension, Renal Insufficiency, and Uremia, but generally speaking, Multiple Renal Cyst has little risk to have these severe complications.
Prevention of the two kinds of disease need to be done from different aspects. Cysts in Polycystic Kidney Disease can be restrained as well as remit the symptoms, while the other one can remove the cyst if it does not have a big size.

What is the Most Effective Way to Lower Creatinine Level?

It is easy for the patients to get various medicines with the function of decrease the creatinine level, such as uremic clearance granule and tablet of creatinine. These medicines are able to excrete the toxins via the intestinal tract or the double function of adsorption and reparation in a rapid way, which is why many patients can see the lowering of the creatinine level obviously after taking the medicine. However, one the medicines are stopped, the creatinine level gets higher again.

Take dialysis.

The basic principle of dialysis is to purify the blood circulation by eliminating the toxins in it, which is similar to that of the medicines. Nevertheless, dialysis is more direct than medicines with a more effective result in the short term, especially for those who are suffering from the complications of Uremia and Diabetic Nephropathy.

Both medicines and dialysis achieve their purpose for short run without any move to repair the renal function, as a result, the creatinine level grow up quickly after stopping the treatment. Bit by bit, the renal function keep losing and the disease is aggravated.

Micro-Chinese Medicine Osmotherapy.

Different with the other two therapies, Micro-Chinese Medicine Osmotherapy directs at regaining the glomerular filtration rate (GFR) which is a sign of renal function, and finally makes the kidneys expel the creatinine by themselves. This theory is similar to the proverb “give a person with the fish, be inferior to giving a person with fishing”. The Chinese Medicine tries to adjust the systemic immune function and repair the basilar membrane of glomeruli, thus the effective elements in the medicine can get into the body via the acupoints and improve the microcirculation as well as the metabolism in the kidneys. After the medicine playing a part in the body, the abnormal data of the kidney can be turned over and the renal function recovered.

Polycystic Kidney Disease

Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.

Autosomal Dominant PKD is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.

Patients get ADPKD from their parents, which means that they are carrying the factors of the disease from the very beginning of their life, but their disease can be found after they grow up. ADPKD can attack a family easily due to its character of heredity. Half of the children may have the disease if one of the parents has PKD, and the percentage will get up to 75% if both of parents have the disease. This is also a key factor which should be noticed, if one of the family members has PKD, other members should be careful and try to delay the occurrence of it.

Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.

What are the Causes of Renal Failure

Kinds of Nephritis can lead to chronic renal failure if the disease can not be treated well in their early stage, for example, Primary Glomerular Nephritis (GN), Mesangial proliferative GN, Acute Glomerular Nephritis, Membraneous Nephritis, and Focal Segmental Glomerular Sclerosis.

Renal Failure can be the secondary disease of Systemic Disease including Hypertension, SLE, Allergic Purpura Nephritis, Diabetes and so on.

III. Infective diseases of Chronic Kidney Disease: Chronic Pyelonephritis, etc.

Chronic Urinary Tract Obstruction is one of the reasons for Renal Failure. Manifestations may include Renal Stone, Double Side of Ureteral Calculi, stenosis of the urinary tract, prostatic hyperplasia and tomours.

Renal failure can result from Congenital Kidney Disease such as PKD, Hereditary Nephritis and some other inherited diseases in the renal tubules.

Other reasons. Taking Renal Toxicity medicines and losing weight blindly and other reasons.

Even though there are many kinds of physical changes in the organs and tissues can be causes of Renal Failure, the result of renal failure is always the same, and the patients will have to take dialysis or kidney transplant to control the disease. If we can block the process of kidney disease at the very beginning, we can do great help in controlling the disease, and that is also why the doctors and the experts call us to discover the disease as early as possible all day long.

How can You Judge Whether You Have Got Kidney Cyst

I. Pain in the waist or stomach.

The tension of renal capsular surface will increase with the expansion of the kidneys, by which the renal pedicle and the adjacent organs will be stretched, and finally make you feel pain. In addition, the cysts make too much water remain in the kidneys and make the kidneys become heavy and be dropped down, which is also a cause of the pain.

Pain caused by kidney cyst is dull, and it is always in a certain part of the body with the possibility of one side or two. However, the pain will be sharpened if capsule hemorrhage or infection happen, and renal colic can be arose by merged stone and clottage.

II. Hematuria.

Both microscopic hematuria and gross hematuria are possible, and they can present periodically. Once hematuria appears, the pain in the waist can be aggravated and itself can also be sharpened by strenuous exercise, wound as well as infection. Hematuria is mainly a consequence of rupture of the artery under the wall of cyst and infection.

III. Lump in the abdomen.

60%-80% of the patients can have tumid kidneys after getting renal cyst and this is also one of the direct reasons which lead people to go to the hospital. Generally speaking, the bigger the cyst is, the severer the disease will be.

What are the Symptoms of Polycystic Kidney Disease?

Swelling in kidney. The disease condition of both kidney differs from each other. The two kidneys will have different sizes and they can occupy all the space in abdomen in the later period of the disease. There are many cysts in the kidney, so the kidney will have irregular shapes and a hard texture.

Pain in renal region. Usually the sufferers will have pressed feeling and dull pain in loin or abdomen. The pain will appear or aggravate after hard work, long-time walking and sitting, and it will release after a rest in bed.

Hematuria. About half of the sufferers will have microscopic hematuria, and sometimes it is gross hematuria. Hematuria is caused by the rupture of blood vessels in cysts' wall, and it is always accompanied with proteinuria, but the volume of urinary protein is small (<1.0g/d). Besides, the pyuria will be obvious when there is infection in the kidney.

Hypertension. Before the increase of serum creatinine, half of sufferers will have Hypertension. It is related to the renin-angiotensin-aldosterone system (RAAS). Hypertension will have influence on the prognosis of sufferers with renal cysts.

Renal insufficiency. Generally speaking, only a few people can have renal insufficiency in the age younger than 40, and about half of the sufferers with PKD will retain their renal function at the age of 70. However, in some cases, the sufferers will deteriorate into renal failure during the adolescence.

Polycystic liver. People who are diagnosed as ADPKD in their middle ages are usually accompanied with Polycystic Liver. Generally speaking, polycystic liver will appear 10 years later after PKD. Besides, sometimes there may be cysts in pancreas and ovary as well.

Acquired Renal Cystic Disease

Acquired Renal Cystic Disease (ARCD) do not relate to age but the years of dialysis. Generally speaking, patients who have dialyzed for more than three years are likely to get Acquired Renal Cystic. there may be three or more cysts in each kidney with a small size about 2-3cm, some of them may lead to infection or even cancer.

Why do patients get ARCD?

As we all know, patients who need to take dialysis must have to the end stage of Chronic Kidney Disease, which means that their renal function have been damaged a lot. The sharp decrease of nephrons can stimulate the kidneys to produce growth factors which are able to help the proliferation of glomeruli, renal tubule and concentrated pipe, thus causing obstruction in the tubules and gradually forming renal cyst. ARCD is not caused by dialysis, but is a complication of renal failure.

Effective Treatment for Renal Cysts

Small cysts will lead to little clinical manifestations. Nowadays there are more people getting renal cysts because of the wide use of B ultrasonic. And those who have simple renal cysts are the most commonly-seen in clinical cases. If the sufferers do not pay any attention to cysts, the cysts will grow bigger gradually and constantly, and the number of cysts will grow with age. If there is no effective treatment, the condition will deteriorate quickly then, leading to renal atrophy and Renal Failure.
In the past, surgical operation is always used to treat Renal Cyst. The common method in treating Renal Cyst is to have a puncture on big cyst. However, the elimination of big cysts provides a growth space for small ones, and there will easily be infections and traumas. At present, stem cells are used into medical field and the effect of stem cell transplantation has been proved by thousands of clinical cases. During the early stage, big cysts can be effectively controlled a avoiding the possible appearance of Renal Failure and Uremia; small cysts can be lessened or eliminated so as to reduce the pressure on surrounding tissues. In this way, renal fibrosis can be prevented and damaged renal tissue repaired, so the renal function can be regained maximally.

How can You Judge Whether You Have Got Kidney Cyst

I. Pain in the waist or stomach.

Pain caused by kidney cyst is dull, and it is always in a certain part of the body with the possibility of one side or two. However, the pain will be sharpened if capsule hemorrhage or infection happen, and renal colic can be arose by merged stone and clottage.

II. Hematuria.

III. Lump in the abdomen.

What causes PKD?

The pathological changes of Polycystic Kidney Disease PKD are: autosome dominant inheritance transformed the phenotype of the epithelial cells in nephridial tubule into epithelial cells in cyst wall. Constantly sac liquid made the cysts become bigger and bigger, and then the normal structure in the kidney be replaced by the cysts, the parclose function of glomerulus decreases as well as the concentration, reabsorption, regulation function in nephridial tubule. Therefore, we can find some signs such as protein and occult blood when we do routine urinalysis, and PKD is in fact a kind of Renal Tubular Epithelial Cell Disease.

Tell You More about Oliguria and Acute Renal Failure

Maybe you have already known that the Acute Renal Failure (ARF) can be divided into three stages, say, the Stage of Oliguria, Diuresis and Recovery. If you are newly diagnosed with this disease, it may possibly in the stage of Oliguria. To know Oliguria, we should firstly have some knowledge of urine. For normal people, the urine volume in a day (24h) is 1500-2000ml. When the urine volume is less than 400ml/d (or 17ml/h), it can be called Oliguria, and when less than 100ml/d (or 4ml/h), Anuria.

How can you know which stage you are in? Now let's have a look at the clinical manifestations of Acute Renal Failure.

1. Oliguria always appears after the precursory signs and will last for 2-4 weeks.

2. You may have a series of malaise such as poorer appetite, nausea, vomit, diarrhea, hiccup, dizziness, headache, short breath and even spasm and coma.

3. You will have Metabolic Acidosis, which is caused by the accumulation of metabolic wastes in your body; the value of serum creatinine (SCr) and Blood Urea Nitrogen (BUN) will rise as well.

4. Disordered electrolyte appears, including hyperkalemia, low serum sodium, high serum phosphate and hypocalcemia, etc. In some cases even the cardiac arrest may appear.

5. Excessive water will remain in human body, so encephaledema or pneumonedema may appear.

In the Acute Renal Failure, renal function decreases progressively and the damages on kidney is deteriorate rather quickly, so there will be various complications during the process. Some common ones are introduced here for your reference.

Life Expectancy for Patients with Renal Failure

The latest nephritic pathological findings show that renal failure still has a chance to get reversed, if patients condition have not aggravate into ESRF( end stage renal failure) and their GFR (glomerular filtration rate) is still more than 20%. In clinical manifestations, whether death from renal failure can be interrupted mainly lies in below factors:
1. The status of urination in a day has a close association with your prognosis.
2. The severity of complications has a direct link with your life expectancy.
3. Whether you can take proper and prompt treatment is the crux to make your condition reverse.
If patients still have urine output, it evinces that their kidneys still have some function remaining. Provided these remaining renal function can be protected, proper treatment can help improve some more functions, patients are probably to prolong the dialysis intervals and even get rid of dialysis. This is of great treatment significance for patients. In most cases, patients do not die from renal failure, but various complications adjoint with renal failure. The earlier you take treatment, the easier your condition can reverse, but the premise is the treatment must me correct or else, your renal condition is probably delayed and exacerbated.
In early stage of renal failure, plasma creatinine does not increase too much. In this stage, they have great chance to get reversed and avoid annoying dialysis if proper and prompt treatment given. On the contrary, if no proper and timely treatment, their condition would be exacerbated and aggravate into Uremia (ESRF). In that case, the ensuing treatment would be quite difficult. Besides, the final treatment effect is involved in individuals’constitution as well. In addition, patients with renal failure should pay attention to their daily life, keep away from cold and anger as well as light diet is recommended. The last but not least is patients must have the confidence to conquer this disease. If you can do this, your improvement and recovery can be expected completely.
Admittedly, there are still some patients with severe condition, common treatment can not help them stop the deterioration of renal function. In this case, they should take sympathetic treatment to remove clinical discomforts at first. Moreover, they should try their best to restore their renal function. Through proper treatment, their condition can be kept stable. Patients can lead a normal life though they still have kidney problems.
Patients with renal failure must not feel depressed after many times failure. Medical science is advancing day by day, as long as you survive one more day, you are probably get saved by updated treatment. This is a truth being witnessed for many times around us.

How to teat Renal Failure?

According to the statistical data made by International Association of Kidney Disease, there are 98-198 patients with chronic renal failure in each million people, and the number in America is 802 and Japan 996. Most patients will wait for kidney transplant which is so expensive that many middle class families may become the poor one.

What's more, after the transplantation of kidney, the patients will have to take medicines to reduce the side effects and reaction in the body. Some patients can live seven years or so with the new kidney, and others longer or shorter.

Is Chronic Nephritis Reversible?

Ms. Bian, a 33-year-old woman, is a sufferer with Chronic Nephritis.
Admitting condition: when she came to Kidney Disease Hospital, a careful examination has been done, which presented: urinary protein 3+, occult blood 1+, 24hUpr 9.15g, together with serious swelling all over the body. She received hormone treatment at that time.
Treatment: she was infused with cord blood stem cells on November 16th, 2010, and then she was given the injection with energy group. Two days after the transplant, she felt discomfortable in the whole body, and have a slight fatigue and headache. She was sleepy all day and her legs were very weak to walk. However, five days later, all the symptoms began to remit gradually and urine examination became normal therewith.
Comments by expert: in some cases, sufferers may have such kind of symptoms after they receive the stem cells transplantation. Some may feel an increase of appetite, have fatigue of different degree, tend to sweat more and have a ruddy complexion; others may have slightly stuffy nose and headache, which are just like the symptoms in a common cold, while those manifestations usually disappear some days later. In clinic, every receiver will be treated separately.
The appearance of urinary protein and occult blood in Chronic Nephritis is caused by damaged intrinsic cells especially epithelial cells and endothelial cells. So there are obstructions in mechanical barriers and charge barriers, and a large amount of protein and red blood cells will be excreted outside the body along with urine.

How to treat PKD?

There is no such a therapy which can curethe disease totally at present,all the therapies are trying to control the disease and help the patients to live a longer life with a higher quality.

A. Operation therapy.

In western country, two kinds of operations called laparoscopic renal cyst decortieation (LRCD) and paracentesisare widely used for the PKD sufferers. By this way, the pain in the body can be released temporarily, but the cysts will recur after several months.

B. Transplantation of kidneys.

Many people think this is a way to help them stop suffering the disease. However, the things can not beas easy as people think. This is just like we throw out a bag of rubbish in the room, but we have to change another bag few days later as long as we are living there and producing rubbish. A new kidney certainly can help the patients’ live a longer life, but it is not always the best way. The patients will have to go and check the body in a regular time; meanwhile, they have to take some medicines to avoid the rejection.

C. Chinese Medicine.

Chinese Medicine can have effective effects on this disease by herbs. The medicine can play a role in the kidney just by external treatment, such as a medical bath without pain. However, the treatment may be a little bit longer and the patients have to be patient enough during the process.

D. Stem cells transplantation.

This is an advanced technology in the medical field. The scientists have proved that stem cells have a function in treating human diseases. The clinical practices in Kidney Disease Hospital also show us a good example. Even so, there are many people do not believe this method and are afraid of the side effects. However, the scientists have proved that stem cells are the primary cells of the body. They can act as many kinds of specific functions in every organ and tissue without any side effects.

What are the Symptoms of Polycystic Kidney Disease?

Swelling in kidney. The disease condition of both kidney differs from each other. The two kidneys will have different sizes and they can occupy all the space in abdomen in the later period of the disease. There are many cysts in the kidney, so the kidney will have irregular shapes and a hard texture.

There are all the common symptoms of Polycystic Kidney Disease. I hope all the information above can be helpful for you. PKD is a genetic disease, so if you have the familial history of PKD, you should have examinations regularly. As long as you have some clinical symptoms, you had better go and see a doctor in order to have a proper treatment in time. If you have any questions, you are welcome to talk with our consultant online or leave a message to ckdsite@hotmail.com .

Five Symptoms of Polycystic Kidney Disease

Anemia: For most of the patients with Polycystic Kidney Disease, they will experience the process from mild anemia to serious anemia and meanwhile, this process is usually accompanied with nocturia. The appearance of this process has great affinity for the decrease of renal function and erythropoietin which is produced by kidneys.

Lump in Abdomen: Patients with Polycystic Kidney Disease can feel the different size of lumps in midsection when kidneys enlarge to a certain degree. These lumps can move with the breath and when these lumps cause infections, patients with Polycystic Kidney Disease will feel pain in their belly. About fifty percent to eighty percent of patients have bilateral pumps and fifteen percent to thirty percent of patients can feel unilateral lumps.

High blood pressure: High blood pressure is one of the common symptoms for patients with Polycystic Kidney Disease, and usually fifty percent to sixty percent of patients have this symptom. High blood pressure usually is prior to the decrease of renal function and is accompanied with headache and dizziness. Blood pressure has a close relationship with type Ⅱ angiotension which is aimed at shrinking blood vessels. When renal function is damaged, renin in our body increase, which will promote the generation of type Ⅱangiotension, leading to the increase of blood pressure.

Discomfort of waist and belly: Usually, discomfort of waist and belly appears in the early stage of Polycystic Kidney Disease. It mainly manifest with dull pain of back and sometimes severe pain.

Brief Introduction of Polycystic Kidney Disease

● Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.

● Autosomal Dominant PKD (ADPKD) is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.

Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.

Can Patients with Polycystic Kidney Disease Drink Wine

Some experts have proved that patients with PKD are strongly suggested to cut out wine. This is mainly for protecting their kidneys as well as their general health. Wine can stimulate the liveness of protein in the cysts, and speed up the secretion of sac liquid as well as the growth of the cysts, thus damaging the renal function quickly.

In addition, the recovery of PKD needs a fine environment in the body. Frequently drinking will arise many problems in the body:

● Increase the blood pressure

● Reduce the bound water in the cells

● Rise the level of creatinine

● Lead to metabolic acidosis symbolized by vomiting, nausea, poor appetite, blue spirit and headache and so on.

● Anemia and disorder of the functions of soterocyte which can lead to bleeding.

● Poor gastrointestinal absorption ability which is the reason of depressed absorption rate of Vitamin B1 and B2 as well as increased excretion of Vitamin B6.

Is Polycystic Kidney Disease (PKD) Curable

As the very question cared by all the patients and the medical learners, this question has been asked again and again.

However, there is no certain word can be the answer, and the majority of the doctors regard the disease incurable. In such a case, what should the patients with PKD do? How can they feel better and live a longer time with the disease?

Doctors in Kidney Disease Hospital studied this question for years, and they are trying to change the life of the patients. What have they done and what will they do?

From the year 2008 to 2011, the doctors in Kidney Disease Hospital have treated all together 1052 cases of PKD which occupies 6.44% of all the patients they have treated in the three years. Moreover, in the following years, they are trying to treat more and more patients with PKD with the only goal which is to help the PKD sufferers feel less pain and live a normal life with the disease.

How can they achieve this goal?

Believe it or not, most of the 1052 patients were treated by the characteristic therapy in Kidney Disease Hospital, namely, Micro-Chinese Medicine Osmotherapy plus Stem Cell Transplant.

These two therapies work together to fight against PKD with special and effective effects. The main theory of them is in three steps.

1. Micro-Chinese Medicine Osmotherapy creates a fine micro-environment in the body by the curative effects of Chinese medicine. It can help to control the growth of the cysts and make a preparation for the stem cells in the next step for a better effect.

2. After the fine micro-environment in the body was built up, the stem cells which are mainly from the umbilical cord blood can be transfused into the patient’s body. Stem cells are the strong power for the reparation of intrinsic cells of the kidneys and the rebuilding of immune system.

3. The two steps mentioned above can act out the function of controlling the growth of the cysts and even shrink the cysts in the body, but the effects should be consolidated by a long-term using of Micro-Chinese Medicine Osmotherapy since Chinese medicine always have better effects in a long run.

Have You Got Renal Cyst

I. Frequent urination and trouble urinating

This is one of the most common reasons for many people to discover renal cysts. After getting the renal cysts, you may find something wrong about urine, such as frequent urination, color changes of the urine, and too much or less urine in several days, then you can go and check your kidneys.

II. Pain in waist and stomach.

Usually people go to the hospital for a physical check when they cannot bear the pain or the pain last for a long time, which will delay the treatment invisibly because at that time the disease is likely in a severe state.

Pain in the waist and stomach is always dull and will be aggravated by infection or bleeding of the cyst. Moreover, if there is a stone in the kidney, cramp pain will occur.

III. Abnormal in the physical report.

With renal cyst, if you go and do the physical test in the hospital, you may find the abnormal of protein quantity and hematuria. Generally speaking, the protein quantity in the urine is less than 2g per hour without the risk of developing into Nephritic Syndrome. As for hematuria, it may appear under the influence of some inducements such as overstrain, cold, pharyngitis and amygdalitis, and it will disappear spontaneously after several hours or one week.

In addition, some patients may also suffer from high blood pressure and decrease of renal function.

How to Treat Hypertensive Nephropathy?

Then, how does high blood pressure damage kidneys? In the early stage, it is the simple hypertension, but when it is not well controlled, the arterial tension rises constantly, and there may be high pressure and great filtration within glomeruli. With the development of hypertension, the structure of renal arteriole is changed so that the blood volume in it decreases, and then ischemia and anoxia of kidneys appear. The endothelial cells in glomeruli are damaged thereby. These damaged endothelial cells promote the accumulation of hematoblast and help to form the thrombus. Some factors will be excreted from them to attract inflammatory cells infiltrate into mesangial regions and damage glomerular functions. Therefore, renal fibrosis begins.

During this period, Renal Insufficiency may happen if the process can not be prevented fundamentally. This is also the reason why Hypertensive Nephropathy reoccurs often in clinic. Western medicine can only reduce the blood pressure and remit the urinary protein, but the root of the disease cannot be treated.

What are the Causes of a High Level of Creatinine

In a simple word, the kidneys just like a sewer for our body which can carry out all the wastes in our body by the way of urine. Creatinine is a kind of metabolic waste which also needs to be excreted out, but if it can not be expelled in time, it will jam the sewer gradually and affect the renal function. Therefore, the level of creatinine can show us the damage in the kidneys. The higher the level is, the severer the disease is.

After knowing the theoretical knowledge of the increase of creatinine level, we can learn some reasons in clinic.

I. People who have renal insufficiency can have an increase of creatinine level in a short time if they are suffering some infections such as cold, pneumonia, enteral infections, urinary tract infections.

II. The serum creatinine level will get higher if the body lacks in water badly, for example, fever, sweet, drink less water, too much urination, less blood flow in the kidneys.

III. Patients with kidney disease who have taken the medicines which are harmful to the kidneys will have to suffer from an increase of creatinine level.

IV. The recurrence of kidney disease causes the changes in the urination, such as less urine or no urine, and if it is combined with acute renal insufficiency, they can lead to the increase of creatinine level.

V. One time increase of creatinine will occur if the patients suffer from overstrain in a long time and do not have enough rest.

VI. If high blood pressure is not controlled well and protein appears in the urine for a long time, the creatinine level can increase gradually.

Blood Urea Nitrogen (BUN) Indicates Kidney Function

Blood Urea Nitrogen is the outcome which is produced along with the metabolism of protein in human body. NH3 and CO2 in liver can be composed into urea (in general, there is 0.3g urea in every gram of protein after the metabolism). Kidney is the main organ that can excrete urea. Urea is filtrated in the glomeruli and is reabsorbed in the renal tubules.

The reference range of BUN in normal adult without food is 3.2-7.1mmol/L (9-20mg/dL in another unit, and this range varies in different regions due to different approaches of detection). In normal condition, the ratio of BUN in serum creatinine is about 10.

The same as serum creatinine, the value of BUN can be an indicator of kidney functions. Usually, when kidney is only damaged slightly, the value of BUN is still in the normal range. Only when the glomerular filtration rate (GFR) is lower than 50%, will the BUN increase obviously. Generally speaking, various kinds of pathological changes in renal parenchyma will make the BUN rises, and there are many influencing factors that can affect the value of BUN. For instance, high-protein diet, water shortage, ischemia of kidney and some types of acute glomerulonephritis will elevate the value of BUN to be as high as 20-30. While, when the intake of protein is too low, or there is something wrong with liver, the value may decrease.

We say above that BUN is related to kidney function, and then, how does it indicate the function?

When the value of BUN increases, we can probably know the organic changes in renal parenchyma, including primary glomerulonephritis, inerstitial nephritis, chronic renal failure caused by polycystic kidney disease, etc. Secondly, it will indicate the prerenal oliguria aroused by mass ascites, failure in heart funtion or pathological changes in liver and so on. At last it may present the excessive intake or decomposition of protein. Meanwhile, when the value of BUN decreases, we can know that there is lesion in renal tubules, because when the filtration function of glomeruli dicreases, the concentration of BUN as well as serum creatinine will stay in the kidneys. However, we can not ensure the disease condition only depend on the sole value of BUN, since diagnosis should be a comprehensive process which requires great responsibility.

Is Multiple Renal Cyst Same with Polycystic Kidney Disease

As one of the most common kidney diseases, Multiple Renal Cyst can occur in people with any ages. Most of the cysts are small and do not have any discomfort, however, there will appear some symptoms if the cysts are larger than 5cm, such as pain in the waist, frequent micturition, urgent urination, odynuria, hematuria.

Nevertheless, Multiple Renal Cyst is not the same with Polycystic Kidney Disease, and there are great differences between them.

◇ The causes and the pathological changes are different. Polycystic Kidney Disease is a kind of autosomal inherited disease, while Multiple Renal Cyst can be inherited or the consequence of wounds, inflammatory reaction, tumour and so on.

◇ Family history is an important factor. There must be some other people who have got similar disease in the family of a patient with Polycystic Kidney Disease, but the patient with Multiple Renal Cyst may not have this problem.

◇ Substance in the cysts are not the same. Urine can always be found in the cysts of Polycystic Kidney Disease, however, the cysts of Multiple Renal Cyst may contain body fluid which is look like plasma and includes red blood cells in it.

◇ Complications are different. Patients with Polycystic Kidney Disease have to suffer from many other diseases, such as Hypertension, Renal Insufficiency, and Uremia, but generally speaking, Multiple Renal Cyst has little risk to have these severe complications.

◇ Prevention of the two kinds of disease need to be done from different aspects. Cysts in Polycystic Kidney Disease can be restrained as well as remit the symptoms, while the other one can remove the cyst if it does not have a big size.

Suggestions to Patients with Hypertensive Nephropathy

Our eating habits have a big influence on our health. For patients with Hypertensive Nephropathy, their diet can influencetheir blood pressure greatly. If patients with Hypertensive Nephropathy want to control their disease effectively, the following principles are necessary.

Ⅰ. Change of dietary habit.

Patients with Hypertensive Nephropathy should analyse their foods under the direction of doctors, so as to find out what foods they can not eat.Only in this way, can the foods meet requirements of their body without aggravating their disease, so as to improve their living quality.

Ⅱ. Control of calorie intake.

Intake value of calorie should depend on the illness condition. Typically, we take the amount that can help to maintain the ideal body weight as the standard. For patients with Hypertensive Nephropathy, they tendto have disorder of lipid metabolism, and the reducing of calories intake not only help to control the heat, but also improve the disorder of metabolism. 　

Ⅲ. Diet with low-salt and high-vitamin

Patients with Hypertensive Nephropathy should control the intake of salt and try to avoid eating salt-preserved foods. Foods added preservatives also should be eaten less. Adequate vitamin, especially vitamin B, is very beneficial in regulating metabolism. Therefore, patients with Hypertensive Nephropathy should try to ingest adequate vitamin and take vitamin supplements if necessary.

What is Diabetic Nephropathy

As a complication of Diabetes, Diabetic Nephropathy (DN) is a kind of diabetic Glomerular sclerosis, particularly refers to the changes in the blood vessels of glomeruli. In the early stage of DN, there is no obvious symptom, and the blood pressure can be under the normal range or higher than that. If the quantity of microalbumin tested by radioimmunoassay is more than 200ug/min, the disease can be called as occulted kidney disease or early stage Nephropathy.

I. Proteinuria.

In the early stage of DN, little quantity of proteinuria can be tested out only with the technology of radioimmunoassay. Proteinuria is the unique sigh of DN in this period, and it will change into a persistence symptom from intermittentl one with the development of the disease.

II. Swelling.

There is always no swelling in the early stage of DN, and some patients may suffer from swelling if the plasma protein will decrease. If there is large quantity of proteinuria or severe edema, the DN must in its late stage.

III. Hypertension.

The morbidity of hypertension in patients with type1 Diabetes is just the same as normal people, but the patients with type2 Diabetes are more likely to get high blood pressure.

IV. Renal Failure.

The progress of the disease in different people is different, some people may have mild degree of proteinuria for years with normal renal function, but some people will have to suffer from Nephrotic Syndrome in several years and Uremia finally.

An Effective Treatment for Renal Failure

The early stage of Renal Failure is a key period in treatment, which can lead to a good result if the opportunity is effectively seized. However, if you have a poor choice of treatment, the later period will be difficult to control and many complications will be caused therewith. Renal fibrosis appears in the early stage, and the original reason of Renal Failure is the damage to renal tissues and the complex of the extracellular matrix. Therefore, the main part of treatment is the repair of damaged tissues in kidneys, and the deterioration of renal fibrosis should be prevented.

You Can Also Get Rid of IgA Nephropathy

Somebody ever said：No matter what God gives you, just accept it. Xia Ying has heard this word, so she accepts the big present, chronic glomerulonephritis, which God gives her. However, should she leave the disease alone? She confused. After several days’ consideration, Xia Ying realized that our lives belong to ourselves and we have rights to cherish it. So Xia Ying began to search information about treating IgA Nephropathy through internet. After comparing those hospitals, Xia Ying finally chose our hospital, Kidney Disease Hospital.
When she arrived at our hospital, we asked her to have a good rest and the second day we arranged a physical examination for her. The result of urine analysis: PRO+2 BLD+3 RBC926.5ul. Besides, there was serious swelling around her eyes. According to her condition, our experts made a unique treatment program for her. Firstly, Xia Ying received Micro-Chinese Medicine Osmotherapy for several days, which can help her remove the most of immune complex of IgA, leading to the disappearance of symptoms such as swelling. And then, she received treatment of stem cell transplant twice. Stem cell transplant, which is very important for her recovery, can help Xia Ying rebuild immunity. At the same, we offered her some western medicines as assistant treatment.

What causes PKD?

The pathological changes of PKD are: autosome dominant inheritance transformed the phenotype of the epithelial cells in nephridial tubule into epithelial cells in cyst wall. Constantly sac liquid made the cysts become bigger and bigger, and then the normal structure in the kidney be replaced by the cysts, the parclose function of glomerulus decreases as well as the concentration, reabsorption, regulation function in nephridial tubule. Therefore, we can find some signs such as protein and occult blood when we do routine urinalysis, and PKD is in fact a kind of Renal Tubular Epithelial Cell Disease.

What is the real name of PKD?

Polycystic Kidney Disease (PKD) is a traditional way of saying which is a right medical result basing on the traditional diagnostic method. Traditional diagnostic method comes from the histological point of view and is a medical result from the structure of kidney. However, according to the advanced western diagnostic method, the theory of renal pathogenesis has developed from histology to cytology, and the diagnosis of kidney disease has been refined from clinical one to pathological one. Because of this, the scientific diagnosis of kidney disease becomes the analysis of the change in cell’s function basing on the damage in cells. what’s more, from the cytology’s point of view, PKD is a kind of genetic disease with the manifestation of variation hyperplasia in renal tubular epithelial cells.

Can Patients with Polycystic Kidney Disease Drink Wine

Some experts have proved that patients with Polycystic Kidney Disease (PKD) are strongly suggested to cut out wine. This is mainly for protecting their kidneys as well as their general health. Wine can stimulate the liveness of protein in the cysts, and speed up the secretion of sac liquid as well as the growth of the cysts, thus damaging the renal function quickly.

In addition, the recovery of PKD needs a fine environment in the body. Frequently drinking will arise many problems in the body:

● Increase the blood pressure

● Reduce the bound water in the cells

● Rise the level of creatinine

● Lead to metabolic acidosis symbolized by vomiting, nausea, poor appetite, blue spirit and headache and so on.

● Anemia and disorder of the functions of soterocyte which can lead to bleeding.

● Poor gastrointestinal absorption ability which is the reason of depressed absorption rate of Vitamin B1 and B2 as well as increased excretion of Vitamin B6.

What are the Symptoms of Diabetes in Children

Diabetes mellitus, often simply referred to as diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. This high blood sugar produces the classical symptoms of polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).

I. It is difficult to say what kind of people are easy to get Type 1 Diabetes, however, the scientists have found some factors which may lead to Type 2 Diabetes.

▲ Children in a family with Diabetic history.

▲ Children whose mother gets Gestational Diabetes during pregnancy period.

▲ Children who have shown insulin resistance, for example, they may have acanthosis nigricans symbolized by melanosis and hyperkeratosis in the skin of neck, armpit and upper leg.

▲ Children who are excessively fat.

▲ Children who are suffering from some disease which can lead to insulin resistance, such as polycystic ovary syndrome (PCOS).

If one or several lines above are suitable to your children, you should take them to do the check regularly so that an early discovery and prevention can be done.

II. Your Children are in a high risk to get the disease if they have one or several symptoms as following.

◆ Urinating too much times a day, some children even can wet the bed after stopping that for a long time.

◆ Drinking more water daily, and they want to get up at night because of thirsty.

◆ Easy to be hungry even though they have a lot of foods every time. In addition, they would like to take some kinds of food they do not like before.

◆ Sharp decreasing of weight. Some children always try to control their weight in daily life without a satisfying result, however, they can be thin in a very short time if they have Diabetes.

◆ Fatigue. The children prefer to stay at home rather than playing outside, and they are more likely to be squat or sitting down. All these changes may also be found in the children who are very naughty.

◆ Decrease of the eyesight.

◆ Itch in the skin and infection in the urinary system shown by vomiting and stomachache, and a short term blood glucose decreasing may appear.

◆ The wound in the children may be difficult to recover, and the wound is easy to be infected and bleeded.

◆ Systems of ketosis acidosis, such as nausea, vomiting, pain in the stomach, lethargy, obnubilation and even coma.

What are the Early Signals of Renal Failure

★ Fatigue and weakness. This is the most difficult one to connect with kidney disease, not even renal failure, and actually, there are so many reasons which will cause kidney problems that no one will think himself/herself to have renal failure. Especially for the young who are busy in working, after they feel better they will forget the illness totally. However, if you feel tired all the day for a long time, it is better for you to talk to your doctors or do some test to make sure that you are in a good condition.

★ Yellow face. This is caused by anemia and will be found easily in men, because a lot of the women think they are anaemic in daily life, and never will they think this is a signal of renal failure.

★ Swelling and edema. Swelling always begins from eyes and the feet, many people also suffer from it in the lower limbs. Swelling is the most obvious signal of kidney disease, once found this problem, go to the hospital and check your body.

★ Urination changes. At first, you may feel like urgent urination, or micturition pain, and your urinary quantity may changes to be too much or too little. At this stage, the toxins in your urine will be less because your renal function has damaged and they can not filter all the wastes out of the body.

★ High blood pressure. We all know that Hypertension can not be cured but can be controlled under a certain stage, once the high blood pressure is in a severe degree or the changes are related to the kidneys, you will have to check your kidneys since renal failure and high blood pressure are interactional.

★ Poor appetite. Because the toxins retained in the body, the function of digestive tract will be influenced, and then the patients may feel not like to eat anything. Some people even feel like nausea and vomiting.

How to Reduce the Creatinine Level

Diabetic Nephropathy is a term indicates kidney function decline in Diabetes patients. The first clue of Diabetic Nephropathy could be Micro-albumin, and then together with disease progression, there will be the increase of creatinine level. High creatinine level indicates to serious kidney function decline.

According to the western therapy and the traditional method, a decrease of creatinine can be achieved by taking medicines; nevertheless, a rebound can be seen once the medicines are stopped, so does the disease condition. If the patients deal with high creatinine in this way, they will suffer a lot both from the high recurrence of the disease and complications caused by the side effects.

The experts of kidney disease point out that a high creatinine is a sign of the decrease of renal function with which the kidneys can excrete less toxins and wastes in the body. Once the kidneys are damaged, there are some other symptoms except high creatinine level, high urea nitrogen and low Glomerular Filtration Rate (GFR), for example, high blood pressure, swellings and edemas, and proteinuria. Therefore, to recover renal health is the root for the treatment of all these changes including high creatinine level.

After more than twenty years' study, doctors in Kidney Disease Hospital have invented a new therapy which can achieve the goal of treating kidney disease fundamentally called Micro-Chinese Medicine Osmotherapy.

By this therapy, the effective element in the Chinese medicine can be permeated into the damaged part in the kidneys externally, and then they will make a difference in our body.

Firstly, they can dilate the blood vessels and promote the microcirculation so that the state of ischemia can be remitted.

Secondly, through the curative effects of anti-inflammatory and anticoagulation, Micro-Chinese Medicine can fight against the process of the disease and block the damage in the kidneys.

Finally, after reducing the wastes and stopping the changes, the medicine can also help to reconstruct the kidney function by stimulating the inactive factors in the kidneys and make the renal unit be strong enough to work for the unary system as well as the whole body. Step by step, the renal function can be recovered, and the high creatinine level can be reduced.

A Recovered Case of Renal Cysts

History of disease: On May 23rd, 2005, she felt fatigue and had loin pain. She went to the local hospital and cysts were detected there. The size of the biggest cyst was 6.2cm×5.8cm×4.0cm. Then she had surgical operation of puncture. Half a month later, clinical manifestations disappeared. Good time was always short, and she had malaise several months later. Then she had operations for another time. However, cysts reoccurred again and again until she can not take care of herself. In June, 2006, she had nausea and vomit, and she can not take food. Then she came to Kidney Disease Hospital.
Admitting conditions: slight high blood pressure, heavy pain and acidosis; serum creatinine: 175umol/L, BUN 12.9 mmol/L, Urinary protein 2+, 24hUpr: 0.29g. The B ultrasonic showed: left kidney 19.0cm×9.2cm, right kidney 20.5cm×12cm.
Treatment: she was infused after the examination and discussion by experts, and Micro-Chinese Medicine Osmotherapy was used at the same time as an assistant therapy.
Follow-up conditions: serum creatinine 125 umol/L, BUN 8.5mmol/L, urinary protein-, 24hUpr 0.16g, left kidney 14.1×6.0cm, right kidney 14.8×5.5cm. Four months later, she had no discomfort and no pain.

Renal Failure

Chronic Renal Failure is a kind of chronic renal parenchymal damage the (real damage in kidney) which can make the kidney shrink obviously so that the kidney cannot work well; it is caused by various reasons. Manifestations of the disease may be a series of symptoms represented by retention of metabolites, the imbalance of water, electrolyte, and acid-base, and involved in systems of the whole body.

When the serum creatinine (Scr) is more than 442μmol/L, the Creatinine Clearance Rate (Ccr) is less than 25ml/min, then the disease can be diagnosed.

At present, Renal Failure can not be cured in the whole world. There are only some ways to control the disease and slow its moving into Uremia, among which dialysis is the most popular one in the patients. Many people have to suffer dialysis daily or weekly in order to have a longer life.

Signs of Diabetic Nephropathy

Firstly, Diabetics may get up for the bathroom more often at night.

Secondly, proteinuria is also an earliest sign of DN.

Thirdly, High blood pressure is also one of the main symptoms of DN. Among the patients with Type 1 Diabetes, the morbidity of Hypertension is same with that among normal people, while the patients with Type 2 Diabetes may suffer a higher risk of getting high blood pressure. In addition, patients with proteinuria are also easily to get Hypertension.