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显示标签为“Polycystic Kidney Disease”的博文。显示所有博文

Polycystic kidney disease complicated by urinary tract infection, hematuria how to do?


What are the complications of polycystic kidney disease, polycystic kidney disease incidence is rising, sometimes bleeding suddenly occurs, can cause pain, bleeding from the cyst walls of cancer associated with cyst. In the positive treatment of polycystic kidney disease, while very effective to prevent, inhibit the occurrence of complications is very important. Polycystic kidney complications which it:
1, urinary tract infection: polycystic kidney complications including cystitis, pyelonephritis, cysts, infections and renal abscess. Women, urinary tract devices check their risk factors. Polycystic kidney complications appear leukocyte urinary tube and conventional anti-infection treatment response quickly favor the diagnosis of pyelonephritis positive blood culture and local tenderness tend cyst infection, CT can be found in infected cyst.
2, kidney stones and kidney calcification: polycystic kidney complications when the pain intensified, combined stones may twist infertility or intraocular hematuria should think.
3 cancerous cyst: cyst whether cancerous so far the issue remains controversial. When the pain the polycystic kidney complications in patients with kidney area or (and) hematuria law changes, weight loss, ESR increase, there does not comply with renal anemia, or polycythemia, polycystic kidney complications should be alert combined kidney cancer, for CT examination in a timely manner, if necessary, need for renal arteriography.
And close to the lower pole ureter cyst in the kidney, polycystic kidney complications aggravated hydronephrosis, and the oppression of the urine of the renal pelvis can cause back pain. Polycystic kidney complications, such obstruction can also kidney infection.

Female patients with polycystic kidney pregnant, will be passed on to children?


Polycystic kidney disease is a genetic kidney disease, polycystic kidney disease increase with age, the cysts gradually increased, the first performance: lower back pain, high blood pressure, abnormal renal B results, if not timely control kidney cysts continue to increase, and oppression around the renal unit will cause injury to start the process of renal fibrosis, will show as urine tests appear: leakage of protein and blood cells; renal fibrosis process has not been effective in deterring appears elevated serum creatinine or glomerular filtration rate, and ultimately develop into end-stage renal failure.
The nephropathy experts, polycystic kidney disease is not only influenced by genetic factors, and the age of the patient at the same time, the geographical location is also certain. Hereditary polycystic kidney disease can be divided into two types: adult polycystic kidney disease is autosomal dominant infantile polycystic kidney disease is autosomal recessive.
Numerous cysts polycystic kidney Department of the renal cortex and medulla of a hereditary disease. The kidney specialists pointed out that the mode of inheritance can be divided into autosomal dominant polycystic kidney and autosomal recessive polycystic kidney disease.
Adult polycystic kidney disease Genetic incidence of approximately 0.2%, mainly in the kidney cysts, increased development and the number of characterized, often accompanied by other organs cyst formation, most common liver, pancreatic, ovarian, and gastrointestinal tract can also be seen.
Autosomal recessive polycystic kidney genetic rule is: both parents heterozygous and homozygous offspring incidence, the incidence probability of 25%. Gender and racial differences.
The etiology of polycystic kidney disease autosomal dominant polycystic kidney genetic laws: female incidence probability thought; either parent for sick children 50% of cysts gene and the disease, if the parents are sick, the increase in the incidence of children to 75%; sick children do not carry the cysts genes.
So, polycystic kidney disease genetic risk is still high, there are the polycystic kidney women for our children's health, it is best not pregnant.

Polycystic kidney disease whether to have children

Fever urine, polycystic kidney disease whether to have children, and polycystic kidney disease for genetic diseases, renal a congenital abnormalities. Bilateral renal Phi medulla can be involved, but different in degree. Performance in the mode of inheritance is autosomal dominant and autosomal recessive inheritance two. With age or due to various external ...
Fever urine, polycystic kidney disease whether to have children, what is the method of treatment of polycystic kidney disease? Western treatment of polycystic kidney disease, what does? What are the methods of Chinese medicine treatment of polycystic kidney disease? Polycystic kidney disease is a hereditary kidney disease, polycystic kidney disease of the entire kidney covered with large and small cysts, these cysts increases with age while growing up, so will the oppression of the kidney, so that the structure of the kidney damage, reduce the production of urine nephron number and later kidney damage can not maintain a normal life, will appear uremia. Thus, no matter what polycystic kidney disease treatment should shrink the cyst, under the premise that protection of renal function and reduce cyst compression kidney tissue thereby affecting the kidney function.
Western medicine in the past has been using the surgical treatment of polycystic kidney, just based on the large cysts to eliminate for the purpose, the use of surgical treatment of polycystic kidney disease make it subsided, but a large cyst regression to the small cyst growth space, a small cyst growth has accelerated, the formation of oppression once again to the kidneys. The treatment of this polycystic kidney disease not only can not be completely improved polycystic kidney disease, returned to patients with physical and mental trauma, more importantly, shortly after surgery, usually about six months, the original symptoms of many patients relapse, and will gradually increase, over the past rapid deterioration of renal function.
Western Hospital of the polycystic kidney disease patients have to wait and see attitude, making the treatment of polycystic kidney disease fall into a passive, that is: wait until after the increase of the small cyst surgery, until the time of renal insufficiency, hemodialysis, in this treatment the effect of the method, the polycystic kidney disease patients are deprived of treatment confidence. The experts concluded that the treatment of polycystic kidney disease is not simply symptomatic treatment, but should start from the pathogenesis of fundamental blocking renal fibrosis.
Blocking renal fibrosis and polycystic kidney disease treatment method, in order to find effective treatment of polycystic kidney disease, you should seize the key of the polycystic kidney disease treatment by polycystic kidney disease renal insufficiency, the uremic the pathogenesis, can The increase seen polycystic kidney disease cyst is uremia caused by the incentive, therefore, whether it is on the treatment of polycystic kidney disease or the treatment of polycystic kidney renal insufficiency, uremia, early the process of blocking renal fibrosis the first priority. Shrink the cysts and protect renal function to get the same height, so that the two reached an effective unified, the only way to be effective polycystic kidney treatment.
Micro therapy for the penetration of traditional Chinese medicine on the basis of the traditional recipe by micronized play activity of traditional Chinese medicine, Chinese medicine treatment is relatively new invasive, painless, patients are more willing to accept medication can eliminate the symptoms, control capsule body development or reduce the thylakoid, stable disease, and renal function returned to normal or near normal, to achieve the purpose of the clinical control.
Gradually recognized in the clinical. After the purpose of such treatment, symptomatic treatment supplemented by Western control in patients with complications, to the treatment of polycystic kidney disease. Many patients with early polycystic kidney disease, take this treatment of polycystic kidney disease, and curb the arrival of uremia; patients with polycystic kidney disease renal failure, late treatment of this polycystic kidney disease, making creatinine gradually decreased, kidney damage is gradually repaired, coupled with the patients to maintain a good attitude, and its condition along with a quick turn for the better.
The content on the treatment of polycystic kidney disease kidney disease hospital of professionals. For the treatment of polycystic kidney disease,  Hospital of kidney disease in addition to the original infiltration therapy of micro-based medicine, but also fully integrated to the forefront of the kidney disease treatment technology, the formation of the reversal of cystic fluid + control shrink the cyst + repair treatment techniques for reconstruction of renal function. Polycystic kidney disease properly controlled completely like a normal person. If you are the related issues of the polycystic kidney disease do not know, to the online expert advice, to control the disease, the most important to protect the kidney function.
Fever urine, polycystic kidney disease whether to have children, it is necessary. The following specifically explain what polycystic kidney disease characteristics.
1, adult polycystic kidney disease from birth, with multiple cysts, but there are many patients has no clinical manifestations, not the disease, they will not use the special treatment.
2, the general to the adult 30 years of age began clinical symptoms, the earlier the age at onset, the more severe clinical symptoms, the later age of onset of clinical symptoms are relatively mild, the male is more important than women.
3, about 30 percent of the polycystic kidney disease patients with polycystic liver, but normal liver function, without any symptoms. Spleen, pancreas, lung, ovarian cysts exist, about 2% of intracranial vascular malformations and aneurysms exist, can easily lead to intracranial hemorrhage.
4, the patient developed symptoms after the general development of renal failure an average of more than 10 years, but there are great individual differences.

Why is high blood pressure?

Why is high blood pressure?  Whether unilateral or bilateral renal parenchymal disease, almost every kind of kidney disease can cause high blood pressure. Glomerulonephritis, lupus nephritis, polycystic kidney disease, congenital renal hypoplasia and other diseases under normal circumstances, if the lesion more extensive and associated with vascular disease or renal ischemia broader, often accompanied by high blood pressure.
Disease causing renal hypertension and detailed description is as follows:
1, primary glomerulonephritis, such as acute glomerulonephritis, rapidly progressive glomerulonephritis, chronic nephritis;
2, secondary glomerulonephritis, lupus nephritis more common;
3, polycystic kidney disease;
4, congenital renal hypoplasia;
5, chronic pyelonephritis;
6 radioactive nephritis;
(7), renal tuberculosis;
8, the huge hydronephrosis;
(9), kidney tumors;
10 kidney stones;
11, renal amyloidosis;
12, Medullary Cystic Disease.
Why is high blood pressure? For example:
Diffuse proliferative glomerulonephritis due to extensive disease and severe renal ischemia, hypertension is extremely common; other hand, minimal change disease, focal proliferative glomerulonephritis and rarely occurs hypertension. Renal tuberculosis, kidney stones, renal amyloidosis, hydronephrosis, simple pyelonephritis, renal medullary cystic disease, and other major performance for lesions of the tubulointerstitial damage of high blood pressure with fewer opportunities. But those diseases are developed to affect the glomerular function often have high blood pressure.
Why is high blood pressure? To sum up the reason proceeds, the incidence of renal hypertension is closely related to the functional status of the glomerulus. Glomerular dysfunction, blood pressure tends to increase, up to 83% of end-stage renal failure incidence of hypertension.

Polycystic Kidney Disease



The Renal Tubular Epithelial Cells would have secreting function when the phenotype of them turns into Cyst Epithelial Cells. Because the cells secrete more and more liquid without normal excretion pathway as the growth of the age, lots of Cyst Fluid is accumulated there. And this results in the enlargement of the cysts, the rise of the pressure in the cysts and the increase of surface tension of it. At this time some sensitive patients would have lumbar unwell and feel sore and bursting. And when part of the cysts is infected, patients would be painful. By the gradual increase of the cysts, the normal structure of the kidney would be replaced, and the function of the kidney begin to decline gradually, which results in Hypertension and abnormal result in test of Urine Routine and renal function.
There are some rules in each Polycystic Kidney Disease stage:
A. Emergence period: the disease is a kind of hereditary disease, and patients always have the cysts inborn which are just too small to be checked out at early stage and it is generally difficult to check out the cysts before the 20s of the patient. If there are the cases of Polycystic Kidney Disease in their family, people should take the examination as early as possible to observe the growth state of the cysts. And they need to take good care of their body.
B. Growth stage: There would be a rapid growth of the cysts when the patient are at the age of 30s to 40s. And we call this period as the growth stage medically. It should be given close observation in growth period. But Western doctors have no method of treatment in this period and they believe the treatment is unnecessary, so what they do is just to conduct symptomatic treatment such as Hypertension and so on, which is quite passive. Patients should positively conduct treatment in this period to stop or slow the cysts’ growth rate by applying the Chinese medicine with the stronger effect of promoting blood circulation and removing blood stasis. And this would meet the purpose to extend the lifetime of the patients. We believe the period is the critical period to slow the growth rate of the cysts by using the Chinese medicine with the effect of promoting blood circulation and removing blood stasis.
C. The swelling period: the cysts would further grow and swell when the patient is in his 40s. In this period the cysts is more than 4cm in size and begin to break up. We call this period as the swelling period. By the enlargement of the cysts, there would be more clinical symptoms such as backache, albuminuria, blood urine, and the increase of blood pressure. We should observe closely in this period. And this period is also the critical period for treament combined with traditional Chinese and western medicine. We could use Chinese medicine to promote blood circulation and remove blood stasis and discharge the toxin of the body, in essence we protect the renal function by getting rid of the cysts liquid which is harmful to the renal function. So the swelling period of Polycystic Kidney is the critical time for the protection of renal function through combined treatment of traditional Chinese medicine and western.

The Stages of Polycystic Kidney Disease

The Stages of PKD can be classified into five stages:
I. Occurrence Stage:Since it is a kind of inherited disease, the patients were born with it. However, due to its small size in the early period, the cysts can be hardly examined when patients are younger than 20 years old. Therefore, if there are Polycystic Kidney Disease cases in family, the patients should take examination as early as possible, in order to observe the development of cyst.
II. Growth Stage: In the patients’30s and 40s, the cysts may develop very fast, medically, we call this period as growth period. In this period, with aggressive treatment, we can stop or stave off the development of cyst with the applications of Micro-Chinese Medicine Osmotherapy to promote blood circulation and remove stasis, and finally, lengthening the PKD patients’ lifespan. Therefore, this period is also a crucial period to treat the disease.
III. Swollen Stage: As the cysts continues to develop, especially when the patients have been 40 years old, the size of cyst will enlarge to over 4cm, and this period before ulceration is called swollen period. With the development of cysts, a series of clinical symptoms will occur, such as backache, albuminuria, hematuria, high blood pressure and so on. However, with effective integration therapy of Chinese Medicine and Western Medicine, the disease development can be controlled.
VI. Rapture Stage: During the development, once affected by various factors, the cysts may get ruptured. Such patients with PKD have to be hospitalized in order to aggressively control infections, or it may arouse sepsis and acute deterioration of renal function.
V. Uremia Stage: Patients with PKD in this period should not lose confidence, because Stem Cell Transplant and Micro-Chinese Medicine Osmostherapy can still help them to protect remained renal functions and prevent the acute deterioration of the disease.

The Early Symptoms of Polycystic Kidney Disease

Bigger kidney
The people in a family with a patient with PKD have more chances of getting PKD. If she or he goes to hospital and takes CT scan, she or he may find the kidney is bigger than normal size. The two kidneys tend to develop in different sizes and different speeds. In early stages, the cysts are usually small and doctors will not suggest those patients adopt any surgeries, but you can feel those cysts if you touch the back of the patients.
Flank pain
The pain in back or side is the most important symptom among patients with PKD. They usually have the feelings of pressure and dull pain in back or side, because the cysts are growing to squeeze other tissues. The pain will be deteriorated by strenuous activities, working or sitting for a long time, but if the sharp pain occurs, PKD may provoke complications such as infection or bleeding cause by cysts being broken.
High blood pressure
It is the most common and persistent symptoms of PKD. Half of those patients are destined to show high blood pressure before serum creatinine getting higher than the normal level. Scientific researches attribute it to cysts’ squeezing the surrounding tissues, activating the release of renin, angiotensin and aldosterone. The medical conditions of the patients with both PKD and high blood pressure will get worse than that of the patients only with PKD.

Polycystic Kidney Disease of treatment

Polycystic Kidney Disease (PKD or PCKD, also known as polycystic kidney syndrome) is a cystic genetic disorder of the kidneys
Although a cure for autosomal dominant PKD is not available, treatment can ease symptoms and prolong life.
Pain. Pain in the area of the kidneys can be caused by cyst infection, bleeding into cysts, kidney stone, or stretching of the fibrous tissue around the kidney with cyst growth. A doctor will first evaluate which of these causes are contributing to the pain to guide treatment. If it is determined to be chronic pain due to cyst expansion, the doctor may initially suggest over-the-counter pain medications, such as aspirin or acetaminophen (Tylenol). Consult your doctor before taking any over-the-counter medication because some may be harmful to the kidneys. For most but not all cases of severe pain due to cyst expansion, surgery to shrink cysts can relieve pain in the back and sides. However, surgery provides only temporary relief and does not slow the disease's progression toward kidney failure.
Headaches that are severe or that seem to feel different from other headaches might be caused by aneurysms-blood vessels that balloon out in spots-in the brain. These aneurysms could rupture, which can have severe consequences. Headaches also can be caused by high blood pressure. People with autosomal dominant PKD should see a doctor if they have severe or recurring headaches-even before considering over-the-counter pain medications.
Urinary tract infections. People with autosomal dominant PKD tend to have frequent urinary tract infections, which can be treated with antibiotics. People with the disease should seek treatment for urinary tract infections immediately because infection can spread from the urinary tract to the cysts in the kidneys. Cyst infections are difficult to treat because many antibiotics do not penetrate the cysts.
High blood pressure. Keeping blood pressure under control can slow the effects of autosomal dominant PKD. Lifestyle changes and various medications can lower high blood pressure. Patients should ask their doctors about such treatments. Sometimes proper diet and exercise are enough to keep blood pressure controlled.
End-stage renal disease. After many years, PKD can cause the kidneys to fail. Because kidneys are essential for life, people with ESRD must seek one of two options for replacing kidney functions: dialysis or transplantation. In hemodialysis, blood is circulated into an external filter, where it is cleaned before re-entering the body; in peritoneal dialysis, a fluid is introduced into the abdomen, where it absorbs wastes and is then removed. Transplantation of healthy kidneys into ESRD patients has become a common and successful procedure. Healthy-non-PKD-kidneys transplanted into PKD patients do not develop cysts.
Although a cure for autosomal dominant PKD is not available, treatment can ease symptoms and prolong life.
Pain. Pain in the area of the kidneys can be caused by cyst infection, bleeding into cysts, kidney stone, or stretching of the fibrous tissue around the kidney with cyst growth. A doctor will first evaluate which of these causes are contributing to the pain to guide treatment. If it is determined to be chronic pain due to cyst expansion, the doctor may initially suggest over-the-counter pain medications, such as aspirin or acetaminophen (Tylenol). Consult your doctor before taking any over-the-counter medication because some may be harmful to the kidneys. For most but not all cases of severe pain due to cyst expansion, surgery to shrink cysts can relieve pain in the back and sides. However, surgery provides only temporary relief and does not slow the disease's progression toward kidney failure.
Headaches that are severe or that seem to feel different from other headaches might be caused by aneurysms-blood vessels that balloon out in spots-in the brain. These aneurysms could rupture, which can have severe consequences. Headaches also can be caused by high blood pressure. People with autosomal dominant PKD should see a doctor if they have severe or recurring headaches-even before considering over-the-counter pain medications.
Urinary tract infections. People with autosomal dominant PKD tend to have frequent urinary tract infections, which can be treated with antibiotics. People with the disease should seek treatment for urinary tract infections immediately because infection can spread from the urinary tract to the cysts in the kidneys. Cyst infections are difficult to treat because many antibiotics do not penetrate the cysts.
High blood pressure. Keeping blood pressure under control can slow the effects of autosomal dominant PKD. Lifestyle changes and various medications can lower high blood pressure. Patients should ask their doctors about such treatments. Sometimes proper diet and exercise are enough to keep blood pressure controlled.
End-stage renal disease. After many years, PKD can cause the kidneys to fail. Because kidneys are essential for life, people with ESRD must seek one of two options for replacing kidney functions: dialysis or transplantation. In hemodialysis, blood is circulated into an external filter, where it is cleaned before re-entering the body; in peritoneal dialysis, a fluid is introduced into the abdomen, where it absorbs wastes and is then removed. Transplantation of healthy kidneys into ESRD patients has become a common and successful procedure. Healthy-non-PKD-kidneys transplanted into PKD patients do not develop cysts.

How Do I Recovery from Polycystic Kidney Disease

This is a real story of my patients.
“I will never forget you, dear.” Ellis replied tearfully, “you are my only in this world”. Hearing this word, I could hardly repress my tears……
I am a young lady with Polycystic Kidney Disease, a genetic kidney disease. I knew I have the potential to get this disease from my childhood. However, when it came that day, I found it is so hard for me to accept this fact. After being diagnosed with Polycystic Kidney Disease, I spend a long time to think about myself, Ellis, and our future. I love Ellis, my smart and handsome husband, and I do not want him to feel sad, but facing this fact, what I can do?
After the fierce ideological struggle, in one morning, I mustered up my courage to told Ellis I have Polycystic Kidney Disease. I hoped he can forget me, however, after hearing his words, I decided to do everything possible to live……
From that day on, I tried every means to treat my disease; however, disappointingly, cysts have never ceased to enlarging. Even so, I will not give up. This month, when I arrived at  Kidney Disease Hospital, my life was changed. I was given Chinese medicine which I do not quite believe before as the major treatment. A week later, I did another examination about my cysts, and when I glanced at the reports, I was shocked. I could hardly breathe. One of my cysts should shrink to 52*45mm mm from 55*46mm. I could not believe what I saw. In order to confirm the authenticity of this report, I did examination again. The fact is the result of two examination reports is same and this time I know I find the chance to lengnow my life.

Is Multiple Renal Cyst Same with Polycystic Kidney Disease

As one of the most common kidney diseases, Multiple Renal Cyst can occur in people with any ages. Most of the cysts are small and do not have any discomfort, however, there will appear some symptoms if the cysts are larger than 5cm, such as pain in the waist, frequent micturition, urgent urination, odynuria, hematuria.
Nevertheless, Multiple Renal Cyst is not the same with Polycystic Kidney Disease, and there are great differences between them.
The causes and the pathological changes are different. Polycystic Kidney Disease is a kind of autosomal inherited disease, while Multiple Renal Cyst can be inherited or the consequence of wounds, inflammatory reaction, tumour and so on.
Family history is an important factor. There must be some other people who have got similar disease in the family of a patient with Polycystic Kidney Disease, but the patient with Multiple Renal Cyst may not have this problem.
Substance in the cysts are not the same. Urine can always be found in the cysts of Polycystic Kidney Disease, however, the cysts of Multiple Renal Cyst may contain body fluid which is look like plasma and includes red blood cells in it.
Complications are different. Patients with Polycystic Kidney Disease have to suffer from many other diseases, such as Hypertension, Renal Insufficiency, and Uremia, but generally speaking, Multiple Renal Cyst has little risk to have these severe complications.
Prevention of the two kinds of disease need to be done from different aspects. Cysts in Polycystic Kidney Disease can be restrained as well as remit the symptoms, while the other one can remove the cyst if it does not have a big size.

Polycystic Kidney Disease

Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.
Autosomal Dominant PKD  is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.
Patients get ADPKD from their parents, which means that they are carrying the factors of the disease from the very beginning of their life, but their disease can be found after they grow up. ADPKD can attack a family easily due to its character of heredity. Half of the children may have the disease if one of the parents has PKD, and the percentage will get up to 75% if both of parents have the disease. This is also a key factor which should be noticed, if one of the family members has PKD, other members should be careful and try to delay the occurrence of it.
Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.

What are the Symptoms of Polycystic Kidney Disease?

Swelling in kidney. The disease condition of both kidney differs from each other. The two kidneys will have different sizes and they can occupy all the space in abdomen in the later period of the disease. There are many cysts in the kidney, so the kidney will have irregular shapes and a hard texture.
Pain in renal region. Usually the sufferers will have pressed feeling and dull pain in loin or abdomen. The pain will appear or aggravate after hard work, long-time walking and sitting, and it will release after a rest in bed.
Hematuria. About half of the sufferers will have microscopic hematuria, and sometimes it is gross hematuria. Hematuria is caused by the rupture of blood vessels in cysts' wall, and it is always accompanied with proteinuria, but the volume of urinary protein is small (<1.0g/d). Besides, the pyuria will be obvious when there is infection in the kidney.
Hypertension. Before the increase of serum creatinine, half of sufferers will have Hypertension. It is related to the renin-angiotensin-aldosterone system (RAAS). Hypertension will have influence on the prognosis of sufferers with renal cysts.
Renal insufficiency. Generally speaking, only a few people can have renal insufficiency in the age younger than 40, and about half of the sufferers with PKD will retain their renal function at the age of 70. However, in some cases, the sufferers will deteriorate into renal failure during the adolescence.
Polycystic liver. People who are diagnosed as ADPKD in their middle ages are usually accompanied with Polycystic Liver. Generally speaking, polycystic liver will appear 10 years later after PKD. Besides, sometimes there may be cysts in pancreas and ovary as well.

What causes PKD?

The pathological changes of Polycystic Kidney Disease PKD are: autosome dominant inheritance transformed the phenotype of the epithelial cells in nephridial tubule into epithelial cells in cyst wall. Constantly sac liquid made the cysts become bigger and bigger, and then the normal structure in the kidney be replaced by the cysts, the parclose function of glomerulus decreases as well as the concentration, reabsorption, regulation function in nephridial tubule. Therefore, we can find some signs such as protein and occult blood when we do routine urinalysis, and PKD is in fact a kind of Renal Tubular Epithelial Cell Disease.

Five Symptoms of Polycystic Kidney Disease

Anemia: For most of the patients with Polycystic Kidney Disease, they will experience the process from mild anemia to serious anemia and meanwhile, this process is usually accompanied with nocturia. The appearance of this process has great affinity for the decrease of renal function and erythropoietin which is produced by kidneys.
Lump in Abdomen: Patients with Polycystic Kidney Disease can feel the different size of lumps in midsection when kidneys enlarge to a certain degree. These lumps can move with the breath and when these lumps cause infections, patients with Polycystic Kidney Disease will feel pain in their belly. About fifty percent to eighty percent of patients have bilateral pumps and fifteen percent to thirty percent of patients can feel unilateral lumps.
 High blood pressure: High blood pressure is one of the common symptoms for patients with Polycystic Kidney Disease, and usually fifty percent to sixty percent of patients have this symptom. High blood pressure usually is prior to the decrease of renal function and is accompanied with headache and dizziness. Blood pressure has a close relationship with type Ⅱ angiotension which is aimed at shrinking blood vessels. When renal function is damaged, renin in our body increase, which will promote the generation of type Ⅱangiotension, leading to the increase of blood pressure.
Discomfort of waist and belly: Usually, discomfort of waist and belly appears in the early stage of Polycystic Kidney Disease. It mainly manifest with dull pain of back and sometimes severe pain.

Brief Introduction of Polycystic Kidney Disease

● Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.
● Autosomal Dominant PKD (ADPKD) is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.
Patients get ADPKD from their parents, which means that they are carrying the factors of the disease from the very beginning of their life, but their disease can be found after they grow up. ADPKD can attack a family easily due to its character of heredity. Half of the children may have the disease if one of the parents has PKD, and the percentage will get up to 75% if both of parents have the disease. This is also a key factor which should be noticed, if one of the family members has PKD, other members should be careful and try to delay the occurrence of it.
Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.

Can Patients with Polycystic Kidney Disease Drink Wine

Some experts have proved that patients with PKD are strongly suggested to cut out wine. This is mainly for protecting their kidneys as well as their general health. Wine can stimulate the liveness of protein in the cysts, and speed up the secretion of sac liquid as well as the growth of the cysts, thus damaging the renal function quickly.
In addition, the recovery of PKD needs a fine environment in the body. Frequently drinking will arise many problems in the body:
● Increase the blood pressure
● Reduce the bound water in the cells
● Rise the level of creatinine
● Lead to metabolic acidosis symbolized by vomiting, nausea, poor appetite, blue spirit and headache and so on.
● Anemia and disorder of the functions of soterocyte which can lead to bleeding.
● Poor gastrointestinal absorption ability which is the reason of depressed absorption rate of Vitamin B1 and B2 as well as increased excretion of Vitamin B6.

Is Multiple Renal Cyst Same with Polycystic Kidney Disease

As one of the most common kidney diseases, Multiple Renal Cyst can occur in people with any ages. Most of the cysts are small and do not have any discomfort, however, there will appear some symptoms if the cysts are larger than 5cm, such as pain in the waist, frequent micturition, urgent urination, odynuria, hematuria.
Nevertheless, Multiple Renal Cyst is not the same with Polycystic Kidney Disease, and there are great differences between them.
◇ The causes and the pathological changes are different. Polycystic Kidney Disease is a kind of autosomal inherited disease, while Multiple Renal Cyst can be inherited or the consequence of wounds, inflammatory reaction, tumour and so on.
◇ Family history is an important factor. There must be some other people who have got similar disease in the family of a patient with Polycystic Kidney Disease, but the patient with Multiple Renal Cyst may not have this problem.
◇ Substance in the cysts are not the same. Urine can always be found in the cysts of Polycystic Kidney Disease, however, the cysts of Multiple Renal Cyst may contain body fluid which is look like plasma and includes red blood cells in it.
◇ Complications are different. Patients with Polycystic Kidney Disease have to suffer from many other diseases, such as Hypertension, Renal Insufficiency, and Uremia, but generally speaking, Multiple Renal Cyst has little risk to have these severe complications.
◇ Prevention of the two kinds of disease need to be done from different aspects. Cysts in Polycystic Kidney Disease can be restrained as well as remit the symptoms, while the other one can remove the cyst if it does not have a big size.

What is the real name of PKD?

Polycystic Kidney Disease (PKD) is a traditional way of saying which is a right medical result basing on the traditional diagnostic method. Traditional diagnostic method comes from the histological point of view and is a medical result from the structure of kidney. However, according to the advanced western diagnostic method, the theory of renal pathogenesis has developed from histology to cytology, and the diagnosis of kidney disease has been refined from clinical one to pathological one. Because of this, the scientific diagnosis of kidney disease becomes the analysis of the change in cell’s function basing on the damage in cells. what’s more, from the cytology’s point of view, PKD is a kind of genetic disease with the manifestation of variation hyperplasia in renal tubular epithelial cells.

Can Patients with Polycystic Kidney Disease Drink Wine

Some experts have proved that patients with Polycystic Kidney Disease (PKD) are strongly suggested to cut out wine. This is mainly for protecting their kidneys as well as their general health. Wine can stimulate the liveness of protein in the cysts, and speed up the secretion of sac liquid as well as the growth of the cysts, thus damaging the renal function quickly.
In addition, the recovery of PKD needs a fine environment in the body. Frequently drinking will arise many problems in the body:
● Increase the blood pressure
● Reduce the bound water in the cells
● Rise the level of creatinine
● Lead to metabolic acidosis symbolized by vomiting, nausea, poor appetite, blue spirit and headache and so on.
● Anemia and disorder of the functions of soterocyte which can lead to bleeding.
● Poor gastrointestinal absorption ability which is the reason of depressed absorption rate of Vitamin B1 and B2 as well as increased excretion of Vitamin B6.

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