Renal insufficiency, hormone therapy: People know that renal insufficiency is often the use of hormone drugs, then the hormone have any therapeutic effect of renal insufficiency? Hormones on renal dysfunction and what side effects? Patients with renal insufficiency have more comprehensive understanding.
Adrenal cortical hormone, referred to as hormone, anti-inflammatory, stable lysosomes, immuno-suppression, increasing the activity of the Department of the glomerular capillary membrane, improving renal insufficiency, glomerular permeability and reduce the leakage of urine protein, so has a diuretic, eliminate protein and protection of renal function in patients with impaired renal function in the role. Large doses of hormones can increase the glomerular filtration rate, and inhibition of antidiuretic hormone, is the drug of choice for Western patients with renal insufficiency, some of the other kidney disease treatment commonly used drugs. But serious side effects may occur in the process of hormone therapy, common side effects are as follows:
(1) infection:
Susceptibility to infection in patients with renal insufficiency in the process of hormone use, and often mask the early symptoms of infection, large doses of hormone therapy should be prevention of infection attention to the pharynx, nose, ears, urinary tract, skin, lungs, abdominal cavity, etc. infection, if found to be infected, the early use of antibiotics.
(2) rows of potassium sodium retention:
Long-term use of hormones in patients with renal insufficiency, attention should be paid to supplement the corresponding amount of potassium salt, eat more fruits and reduce the intake of salt, if necessary, service row natriuretic drug.
(3) acute adrenal insufficiency:
Long-term use of hormone therapy can be caused by endogenous adrenal cortical hormone secretion in patients with renal dysfunction by the inhibition of infection, can cause acute adrenal dysfunction Therefore, patients with renal insufficiency in the process of application of hormone therapy, a doctor under the guidance, not to reduce or stop the medication.
(4) bleeding and gastric perforation:
Merger stomach, duodenal ulcer disease or gastrointestinal bleeding in patients with renal insufficiency, large doses of hormones could easily cause bleeding or perforation, so that those patients with ulcer disease, as far as possible with the use of small doses of hormones and the treatment of ulcer drug, and often Note that the stool color and check for occult blood.
(5) a hypercoagulable state and Thrombosis:
The hormone may increase the tendency of renal insufficiency in patients with a hypercoagulable state and concurrent embolization, Guchang combination of anticoagulants or traditional Chinese medicine. Prevention and treatment of renal vein thrombosis and cerebral embolism.
(6), renal dysfunction and blood pressure:
Hormone treatment of adult patients with renal insufficiency, renal dysfunction, high blood pressure side effects. Therefore, the renal dysfunction associated with nitrogen retention should be used with caution.
Because of the serious side effects of hormone therapy, combined with the hospital experience in clinical practice, it is recommended in patients with kidney disease occurred in the early use of hormone therapy at the same time, we must as soon as possible involved in micro-technology medicine penetrate therapy until the final instead of hormone therapy to reduce or avoid side effects occurred.
Kidney disease experts recommend the use of stem cell transplantation for treatment of kidney disease - the stem cells is a strong self-replicating and multiple differentiation ability to repair cells, it enters the body will be strong to repair damaged cells function in kidney patients, there is a strong recovery of renal function capacity. Therefore, kidney disease for patients with stem cell transplantation is an effective means of treatment. The one hand, the maximum stem cell therapy to repair damaged kidney cells in the lesions of blocking the renal fibrosis process, lower serum creatinine, and reduce the complications of renal anemia, hypertension, renal edema, but also allows protein, occult blood, and other indicators decreased or even negative, can prolong dialysis time interval, or even get rid of dialysis, regulate and control the primary disease. Even in late renal failure, uremia, the implementation of stem cell therapy, are also viable options.Stem cell therapy will be as much as possible as a supplementary treatment to repair damaged kidney cells to protect the residual renal cell, renal function. But also in conjunction with other effective treatment for reversal of lesions occur renal cell dialysis interval to extend and improve the complications, slow down the process of kidney failure, and improve the quality of life
Chronic renal insufficiency can sex of children with renal insufficiency how diagnosed
Children with renal insufficiency how diagnosed? Nephropathy with nephrotic expert experts pointed out that children with renal insufficiency can be divided into simple and the the uremic two children of both cases is slightly different clinical manifestations, and here we take up specific What are the characteristics look at the simple type and uremic type children with renal insufficiency, What are the diagnostic criteria?
How diagnosis of children with renal insufficiency?, Renal insufficiency, "simply type"
1, the massive proteinuria: urinary protein qualitative ≥ + + +, quantitative ≥ 50mg / (kg? D), for two weeks or more;
Hypoproteinemia: serum albumin <30g / L;
Hyperlipidemia: plasma cholesterol ≥ 5.7mmol / L;
4, renal insufficiency, simply type in children with varying degrees of edema;
Children with renal insufficiency how diagnosed?, Renal insufficiency, uremia type "-
Hematuria: 2 weeks three times a urine test, centrifuged urine red blood cells ≥ IO / HP;
2, high blood pressure: school-age children ≥ 130/90mmHg (17.0/12.0kPa), preschool children ≥ 120/80mmHg (16.0/10.7kPa);
Azotemia: blood urea nitrogen (BUN)> 10.70mmol / L;
4, persistent hypocomplementemia (serum complement c3 down).
How diagnosed child with renal insufficiency? Controlled by the above standard, the majority of children with kidney disease to confirm the diagnosis, develop a reasonable treatment options, speedy recovery so that children with kidney disease.
Infiltration therapy of micro-based traditional Chinese medicine, mainly through a few have made the treatment of diabetic nephropathy treatment of small effect
A "vasodilator" utility: alleviate hypertension status and vascular tension, to prevent damage of hypertensive renal vascular endothelial cells and promote blood circulation, at the same time, can also be effective to improve the digestive system, microcirculation, alleviate gastrointestinal mucosal edema caused by kidney disease, to promote an increase in the secretion of digestive juice, increase appetite.
(2) anti-inflammatory action principle: hypertensive nephropathy and other types of kidney disease, its anti-inflammatory capacity decreased by the infection of bacteria, viruses, and due to vascular ischemia, hypoxia, resulting in damage to the local kidney microcirculation itself anti-inflammatory decreased ability to damage the kidney vascular endothelial cells, dynamic balance function has been disrupted, and attract inflammatory cell infiltration in the blood circulation, the formation of the inflammatory response and start of renal fibrosis.
"Anticoagulant" principle: the treatment of hypertensive nephropathy can not neglect the anticoagulant therapy. As the long-term high blood pressure damage the kidneys, produce microcirculation, resulting in the state of ischemia and hypoxia, damage renal vascular endothelial cells, anticoagulant activity, and promote platelet adhesion and aggregation, and microthrombosis. Micro-thrombosis will further aggravate renal ischemia and hypoxia, speed up the process of renal fibrosis.
"Degradation" principle: the degradation of metabolic waste extracellular matrix, is inherent in the nephrotic patients with kidney cells can be reversed, the key to whether the block in renal fibrosis. Kidney patients used in the treatment of Western medicine, Chinese medicine generally does not have this utility, which is also repeated the main reason for attack.
Of traditional Chinese medicine infiltration therapy of active substances into the renal micro directly for lesion accumulation of extracellular matrix removal, such substances will gradually replace the healthy kidney inherent cells, activity of micro-based traditional Chinese medicine material will begin to make fragmentation, degradation excreted. At the same time, but also promote renal synthesis and degradation enzymes and enhance its activity, degradation of extracellular matrix. You turn the intrinsic cells of the lesions occur in the kidney.
How diagnosis of children with renal insufficiency?, Renal insufficiency, "simply type"
1, the massive proteinuria: urinary protein qualitative ≥ + + +, quantitative ≥ 50mg / (kg? D), for two weeks or more;
Hypoproteinemia: serum albumin <30g / L;
Hyperlipidemia: plasma cholesterol ≥ 5.7mmol / L;
4, renal insufficiency, simply type in children with varying degrees of edema;
Children with renal insufficiency how diagnosed?, Renal insufficiency, uremia type "-
Hematuria: 2 weeks three times a urine test, centrifuged urine red blood cells ≥ IO / HP;
2, high blood pressure: school-age children ≥ 130/90mmHg (17.0/12.0kPa), preschool children ≥ 120/80mmHg (16.0/10.7kPa);
Azotemia: blood urea nitrogen (BUN)> 10.70mmol / L;
4, persistent hypocomplementemia (serum complement c3 down).
How diagnosed child with renal insufficiency? Controlled by the above standard, the majority of children with kidney disease to confirm the diagnosis, develop a reasonable treatment options, speedy recovery so that children with kidney disease.
Infiltration therapy of micro-based traditional Chinese medicine, mainly through a few have made the treatment of diabetic nephropathy treatment of small effect
A "vasodilator" utility: alleviate hypertension status and vascular tension, to prevent damage of hypertensive renal vascular endothelial cells and promote blood circulation, at the same time, can also be effective to improve the digestive system, microcirculation, alleviate gastrointestinal mucosal edema caused by kidney disease, to promote an increase in the secretion of digestive juice, increase appetite.
(2) anti-inflammatory action principle: hypertensive nephropathy and other types of kidney disease, its anti-inflammatory capacity decreased by the infection of bacteria, viruses, and due to vascular ischemia, hypoxia, resulting in damage to the local kidney microcirculation itself anti-inflammatory decreased ability to damage the kidney vascular endothelial cells, dynamic balance function has been disrupted, and attract inflammatory cell infiltration in the blood circulation, the formation of the inflammatory response and start of renal fibrosis.
"Anticoagulant" principle: the treatment of hypertensive nephropathy can not neglect the anticoagulant therapy. As the long-term high blood pressure damage the kidneys, produce microcirculation, resulting in the state of ischemia and hypoxia, damage renal vascular endothelial cells, anticoagulant activity, and promote platelet adhesion and aggregation, and microthrombosis. Micro-thrombosis will further aggravate renal ischemia and hypoxia, speed up the process of renal fibrosis.
"Degradation" principle: the degradation of metabolic waste extracellular matrix, is inherent in the nephrotic patients with kidney cells can be reversed, the key to whether the block in renal fibrosis. Kidney patients used in the treatment of Western medicine, Chinese medicine generally does not have this utility, which is also repeated the main reason for attack.
Of traditional Chinese medicine infiltration therapy of active substances into the renal micro directly for lesion accumulation of extracellular matrix removal, such substances will gradually replace the healthy kidney inherent cells, activity of micro-based traditional Chinese medicine material will begin to make fragmentation, degradation excreted. At the same time, but also promote renal synthesis and degradation enzymes and enhance its activity, degradation of extracellular matrix. You turn the intrinsic cells of the lesions occur in the kidney.
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