Children with IgA nephropathy common type of kidney injury

Iga nephropathy the main clinical symptom is hematuria, IgA nephropathy prognosis is poor, is one of the main cause of renal failure, renal injury in IgA nephropathy following types:
First, episodes of gross hematuria
Often in a variety of respiratory tract infections in 1-3d after gross hematuria, it is also known as to pharyngitis synchronous hematuria, this point with the common sense ofacute chain glomerulonephritis. Deformability of urinary red cell morphology, suggesting that glomerular hematuria. I have seen homes in addition to the naked eye hematuria,and in some cases accompanied by the waist and (or) abdominal pain, often misdiagnosed as urinary calculi, acute abdomen (appendicitis). The mechanism of suchabdominal pain may be associated with inflammatory lesions of small arteries in theureter or gastrointestinal mucosa, is a systemic small vessel vasculitis lesions showed. Inaddition, the electron microscope shows submucosal small artery injury was fibrinoidnecrosis, IgA, and C3, and fibrin deposition to support IgAGN gastrointestinal tract has also been compromised. Low back pain associated with urinary retention or temporaryoliguria may be of small blood clots occur in the urinary tract caused by a temporaryobstruction.
Second, the simple proteinuria
Proteinuria as the first symptom in pediatric majority showed symptoms of mild or moderate proteinuria without edema and renal injury.
Third, the nephrotic syndrome
Individually or in some cases associated with hypertension, hematuria. If thehistopathological glomerular sclerosis and renal vascular sclerosis poor prognosis.Shanghai pediatric hospitals reported 20 cases IgAGN, which manifested as nephrotic-type, 9 cases (47%), showing that this type of a certain proportion of children IgAGN.
Fourth, the nephritic syndrome
Microscopic hematuria associated with this type of performance / with asymptomaticmild edema misdiagnosed chain flu glomerulonephritis more common in urine screening examination, and confirmed by biopsy.
Fifth, rapidly progressive glomerulonephritis
Rare. Continuous gross hematuria, large amounts of proteinuria associated with theheart, brain involvement, the abrupt deterioration of short-term renal function, renal biopsyhas extensive (50% -100%) in the form of glomerular crescent. Severe hematuriahemoglobin on renal tubular toxicity and tubular obstruction, acute tubular necrosis.

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