Systemic lupus erythematosus (SLE) is a violation of systemic connective
tissue autoimmune diseases, the lesions often involving multi-system organ.
Lupus nephritis in the kidney is more common, the harm can not be ignored in
patients with lupus nephritis disease, which causes the problem, many patients
are not very clear, then lupus nephritis the cause? please the
nephrotic Hospital Nephrology experts to unlock everyone's doubts, to see if the
experts are introduced, can provide help for patients.
The experts tell us that lupus nephritis is the most common organ damage in
systemic lupus erythematosus. Systemic lupus erythematosus is a violation of
systemic connective tissue autoimmune diseases, lesions often involving
multi-system organ. In Chinese medicine, there is no lupus nephritis in this
disease name. According to their clinical manifestations of this disease
attributable to edema, back pain, sun sores, poison of yin and yang, warm poison
spots, Consumption, dizziness, palpitations and other permit areas.
The cause of lupus nephritis following factors:
(1) genetic factors of the patients have the same disease family history
accounted for 0.4% to 3.4.
(2) the humoral immune changes including DNA and anti-DNA antibodies form
immune complexes play a major role.
Cellular immunity: the suppressor T cell function and decline in the number.
The reason is that the existence of cytotoxic antibody (anti-lymphocyte or
thymocyte antibody) in serum, thereby undermining the T cells.
